ReviewReproductive sciences (Thousand Oaks, Calif.)2010
Gender differences in cardiovascular disease: hormonal and biochemical influences.
Review in Reproductive sciences (Thousand Oaks, Calif.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it, 202 citations in OpenAlex.
- Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.Nature communications · 2021Pooled it
- Salt loading has a more deleterious effect on flow-mediated dilation in salt-resistant men than women.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2014Trial
- Investigation of the Association between Long-term Ozone Exposure and Cardiovascular Disease: A Meta-Analysis Addressing Exposure Windows, Vulnerable Populations, and Spatial Variation.China CDC weekly · 2026Review
- Evolving mortality trends in hypertension-associated ischemic heart disease among U.S. adults over two decades: a CDC wonder analysis (2000-2023).Journal of human hypertension · 2026Article
- Article
- Sex specific pattern of adipose expansion, inflammation and dysfunction with short term high fat diet exposure.Frontiers in endocrinology · 2026Article
- Interaction and biological pathway analysis of proteomic products in patients with premature coronary artery disease.Clinical proteomics · 2025Article
- Triglycerides, Cholesterol, and Depressive Symptoms Among Undergraduate Medical Students: A Cross-Sectional Study.Diseases (Basel, Switzerland) · 2025Article
- Advances in biomonitoring technologies for women's health.Nature communications · 2025Review
- Both Alcoholic and Non-Alcoholic Liver Cirrhosis Are Associated with an Increased Risk of HF-A Cohort Study Including 75,558 Patients.Journal of cardiovascular development and disease · 2025Article
- Triglyceride-glucose-related indices and risk of cardiovascular disease and mortality in individuals with cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3: a prospective cohort study of 282,920 participants in the UK Biobank.Cardiovascular diabetology · 2025Article
- A case-control study of the interaction of the eNOS gene polymorphisms rs1799983 and rs1800780 with acute coronary syndrome (ACS) risk factors.BMC cardiovascular disorders · 2025Article
- Observational
- Review
- Myocardial Bridging, Unusual Cause of Myocardial Infarction; Case Report and Review of Literature.Clinical case reports · 2025Article
- Age and Sex Differences in Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- Use of Polygenic Risk Score for Prediction of Heart Failure in Cancer Survivors.JACC. CardioOncology · 2024Article
- Review
- Gender Matters: A Multidimensional Approach to Optimizing Cardiovascular Health in Women.Cureus · 2024Review
- Dental caries prevalence in relation to the cardiovascular diseases: cross-sectional findings from the Iranian kurdish population.BMC oral health · 2024Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
objectiveAtherosclerosis is a complex process characterized by an increase in vascular wall thickness owing to the accumulation of cells and extracellular matrix between the endothelium and the smooth muscle cell wall. There is evidence that females are at lower risk of developing cardiovascular disease (CVD) as compared to males. This has led to an interest in examining the contribution of genetic background and sex hormones to the development of CVD. The objective of this review is to provide an overview of factors, including those related to gender, that influence CVD.
methodsEvidence analysis from PubMed and individual searches concerning biochemical and endocrine influences and gender differences, which affect the origin and development of CVD.
resultsAlthough still controversial, evidence suggests that hormones including estradiol and androgens are responsible for subtle cardiovascular changes long before the development of overt atherosclerosis.
conclusionExposure to sex hormones throughout an individual's lifespan modulates many endocrine factors involved in atherosclerosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.