ArticleLipids in health and disease2010
Diabetes prediction, lipid accumulation product, and adiposity measures; 6-year follow-up: Tehran lipid and glucose study.
Article in Lipids in health and disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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54 citing papers in PubMed, 119 citations in OpenAlex.
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- Comparative analysis of 16 baseline obesity and lipid-related indices for cardiovascular disease risk prediction in adults with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study.Diabetology & metabolic syndrome · 2025Article
- Prediction of MASLD using different screening indexes in Chinese type 2 diabetes mellitus.Diabetology & metabolic syndrome · 2025Article
- Association between lipid accumulation product and non-alcoholic fatty liver disease with normal weight: a population-based study.Frontiers in medicine · 2025Article
- Optimal obesity- and lipid-related indices for predicting type 2 diabetes in middle-aged and elderly Chinese.Scientific reports · 2024Article
- Article
- The relationship between depression and lipid accumulation product: a population-based study.Frontiers in psychiatry · 2024Article
- Enhanced Predictive Value of Lipid Accumulation Product for Identifying Metabolic Syndrome in the General Population of China.Nutrients · 2023Article
- Article
- Comparison of lipid accumulation product and visceral adiposity index with traditional obesity indices in early-onset type 2 diabetes prediction: a cross-sectional study.Diabetology & metabolic syndrome · 2023Article
- Sex difference in the associations among obesity-related indices with incidence of diabetes mellitus in a large Taiwanese population follow-up study.Frontiers in public health · 2023Article
- The predictive significance of lipid accumulation products for future diabetes in a non-diabetic population from a gender perspective: an analysis using time-dependent receiver operating characteristics.Frontiers in endocrinology · 2023Article
- Data mining approaches for type 2 diabetes mellitus prediction using anthropometric measurements.Journal of clinical laboratory analysis · 2023Article
- Lipid accumulation product, visceral adiposity index and risk of chronic kidney disease.BMC nephrology · 2022Article
- Association of lipid accumulation product with type 2 diabetes mellitus, hypertension, and mortality: a systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2022Review
- Altered Visceral Adipose Tissue Predictors and Women's Health: A Unicenter Study.International journal of environmental research and public health · 2022Article
- Comparison of obesity indices and triglyceride glucose-related parameters to predict type 2 diabetes mellitus among normal-weight elderly in China.Eating and weight disorders : EWD · 2022Article
- Assessment of visceral adiposity index and lipid accumulation product index as markers of chronic kidney disease among diabetic and hypertensive patients at the Bamenda Regional Hospital, Cameroon: a cross-sectional study.The Pan African medical journal · 2022Article
- Association Between Lipid Accumulation Product and Target Organ Damage in Elderly Population: The Northern Shanghai Study.Clinical interventions in aging · 2021Article
- Transition of Lipid Accumulation Product Status and the Risk of Type 2 Diabetes Mellitus in Middle-Aged and Older Chinese: A National Cohort Study.Frontiers in endocrinology · 2021Article
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3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe body mass index (BMI) is the most commonly used marker for evaluating obesity related risks, however, central obesity measures have been proposed to be more informative. Lipid accumulation product (LAP) is an alternative continuous index of lipid accumulation, which is computed from waist circumference (WC, cm) and triglycerides (TGs, mmol/l): (WC-65) xTG (men) and (WC-58) xTG (women). We sought in this study to assess if LAP can outperform BMI, waist-to-height-ratio (WHtR), or waist-to-hip-ratio (WHpR) in identifying prevalent and predicting incident diabetes.
resultsThe cross-sectional analyses were performed on a sample included 3,682 men and 4,989 women who were not pregnant, aged > or = 20 years. According to the age (> or = 50 and <50 years) - and sex-specific analyses, odds ratios (ORs) of LAP for prevalent diabetes were higher than those of BMI, WHpR, or WHtR among women, after adjustment for mean arterial pressure and family history of diabetes. The OR of LAP in old men was lower than those of other adiposity measures; in young men, however, LAP was superior to BMI but identical to WHpR and WHtR in identifying prevalent diabetes. Except in young men, LAP showed highest area under the receiver operating characteristic curves (AROC) for prevalent diabetes (P for trend < or = 0.005). For longitudinal analyses, a total of 5,018 non-diabetic subjects were followed for approximately 6 years. The ORs of BMI, WHpR, and WHtR were the same as those of LAP in both sexes and across age groups; except in young men where LAP was superior to the BMI. AROCs of LAP were relatively the same as anthropometric adiposity measures.
conclusionsLAP was a strong predictor of diabetes and in young individuals had better predictability than did BMI; it was, however, similar to WHpR and WHtR in prediction of incident diabetes.
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