Evidence map›Paper›PMID 20458101›Full record

SynthesisMayo Clinic proceedings2010

Sexual abuse and lifetime diagnosis of psychiatric disorders: systematic review and meta-analysis.

Laura P Chen, M Hassan Murad, Molly L Paras, Kristina M Colbenson, Amelia L Sattler, Erin N Goranson, Mohamed B Elamin, Richard J Seime, Gen Shinozaki, Larry J Prokop and 1 more

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Mayo Clinic proceedings, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 297 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
297citing papers in PubMed, 17 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04859686 nacompletednot on this map

Acupuncture and Meditation for Wellness (AMWELL)

TypeinterventionalSponsorUniformed Services University of the Health SciencesRan2008 to 2010Enrolled77ConditionsPTSDArmsMindfulness-Based Stress Reduction, Acupuncture Treatment
NCT05490121 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluating an Educational Intervention for Improving Residents' Recognition and Response to Child Maltreatment - A Mixed Method Acceptability and Feasibility Study With a Pilot Randomized Trial

TypeinterventionalSponsorMcMaster UniversityRan2022 to 2023Enrolled84ConditionsDomestic Violence, Child Maltreatment, Pediatric ALL, PsychiatryArmsViolence, Evidence, Guidance, Action Project (VEGA) Education Intervention
3 · Its place in the literature

Who cites it

297 citing papers in PubMed, 17 syntheses or guidelines pooled it.

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237 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laura P ChenMayo Medical School, Mayo Clinic, Rochester, MN 55905, USA.
M Hassan Murad
Molly L Paras
Kristina M Colbenson
Amelia L Sattler
Erin N Goranson
Mohamed B Elamin
Richard J Seime
Gen Shinozaki
Larry J Prokop
Ali Zirakzadeh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically assess the evidence for an association between sexual abuse and a lifetime diagnosis of psychiatric disorders. PATIENTS AND

methodsWe performed a comprehensive search (from January 1980-December 2008, all age groups, any language, any population) of 9 databases: MEDLINE, EMBASE, CINAHL, Current Contents, PsycINFO, ACP Journal Club, CCTR, CDSR, and DARE. Controlled vocabulary supplemented with keywords was used to define the concept areas of sexual abuse and psychiatric disorders and was limited to epidemiological studies. Six independent reviewers extracted descriptive, quality, and outcome data from eligible longitudinal studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were pooled across studies by using the random-effects model. The I(2) statistic was used to assess heterogeneity.

resultsThe search yielded 37 eligible studies, 17 case-control and 20 cohort, with 3,162,318 participants. There was a statistically significant association between sexual abuse and a lifetime diagnosis of anxiety disorder (OR, 3.09; 95% CI, 2.43-3.94), depression (OR, 2.66; 95% CI, 2.14-3.30), eating disorders (OR, 2.72; 95% CI, 2.04-3.63), posttraumatic stress disorder (OR, 2.34; 95% CI, 1.59-3.43), sleep disorders (OR, 16.17; 95% CI, 2.06-126.76), and suicide attempts (OR, 4.14; 95% CI, 2.98-5.76). Associations persisted regardless of the victim's sex or the age at which abuse occurred. There was no statistically significant association between sexual abuse and a diagnosis of schizophrenia or somatoform disorders. No longitudinal studies that assessed bipolar disorder or obsessive-compulsive disorder were found. Associations between sexual abuse and depression, eating disorders, and posttraumatic stress disorder were strengthened by a history of rape.

conclusionA history of sexual abuse is associated with an increased risk of a lifetime diagnosis of multiple psychiatric disorders.

Indexed as

AdultAnxiety DisordersCase-Control StudiesChildDepressionEpidemiologic Research DesignFeeding and Eating DisordersFemaleGenetic Predisposition to DiseaseHumansLongitudinal StudiesMaleMental DisordersOdds RatioPrevalenceRisk Factors

Identifiers

PMID20458101
PMCPMC2894717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.