Evidence map›Paper›PMID 20458021›Full record

ReviewCirculation2010

Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies.

Stephen L Archer, E Kenneth Weir, Martin R Wilkins

Abstract readReview
In one paragraph

Review in Circulation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

226 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Endothelin receptor antagonists for pulmonary arterial hypertension.The Cochrane database of systematic reviews · 2013
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Pulmonary hypertension.Nature reviews. Disease primers · 2024
    Review
  18. Review
  19. Article
  20. Article

166 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephen L ArcherUniversity of Chicago, IL 60637, USA. sarcher@medicine.bsd.uchicago.edu
E Kenneth Weir
Martin R Wilkins

Funding

O2 sensing in the human and rabbit ductus arteriosus.R01HL071115 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2004 to 2015
$3.1M
Opposing Modulation of K+ Channels by a Redox SensorR01HL065322 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI WEIR, EDWARD KENNETH · 2001 to 2008
$1.8M
The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial HypertensionR01HL113003 · NHLBI · QUEEN'S UNIVERSITY AT KINGSTON · PI ARCHER, STEPHEN L · 2013 to 2016
$1.1M
Impaired mitochondrial fusion in pulmonary arterial hypertensionRC1HL099462 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2009 to 2010
$1.0M
British Heart FoundationMedical Research CouncilNHLBI NIH HHS 1RC1HL099462-01NHLBI NIH HHS R01 HL065322NHLBI NIH HHS R01 HL071115NHLBI NIH HHS R01-HL071115NHLBI NIH HHS R01 HL113003NHLBI NIH HHS R01 HL 65322NHLBI NIH HHS RC1 HL099462
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiologyAnimalsHeart FailureHumansHypertension, Pulmonary

Identifiers

PMID20458021
PMCPMC2869481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.