Evidence map›Paper›PMID 20457680›Full record

ArticlePediatrics2010

Unilateral hearing loss is associated with worse speech-language scores in children.

Judith E C Lieu, Nancy Tye-Murray, Roanne K Karzon, Jay F Piccirillo

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05106413 (Evaluation of the Clinical Benefit of a Transmitter for Contralateral Routing of Signals), which is not on this map. Cited by 102 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05106413 naterminatednot on this mapstarted 2021, after this paper: background citation

Evaluation of the Clinical Benefit of a Transmitter for Contralateral Routing of Signals (CROS)

TypeinterventionalSponsorSonova AGRan2021 to 2022Enrolled23ConditionsHearing LossArmsBiCROS fitting, Monaural fitting, Unaided condition, CROS baseline
3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 4 syntheses or guidelines pooled it, 329 citations in OpenAlex.

  1. Efficacy of vibrant sound bridge in congenital aural atresia: an updated systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. Pooled it
  3. Cochlear implantation for single-sided deafness: the outcomes. An evidence-based approach.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2014
    Pooled it
  4. Personally Modifiable Risk Factors Associated with Pediatric Hearing Loss: A Systematic Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2014
    Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Assessment of language development in children with prelingual single-sided deafness.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Development and Validation of a Novel Prediction Model for Hearing Loss From Cisplatin Chemotherapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Article
  16. Article
  17. Article
  18. Assessment of the Audiological Profile and Related Risk Factors for Sensorineural Hearing Loss in Children with Speech and Language Delay.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  19. Cochlear Implantation Outcomes in Pediatric Unilateral Hearing Loss: Impact of Device Use and Direct Input.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Judith E C LieuDepartment of Otolaryngology, Head and Neck Surgery, Washington University School of Medicine, St Louis, MO 63110, USA. lieuj@wustl.edu
Nancy Tye-Murray
Roanne K Karzon
Jay F Piccirillo
Washington University in St. Louis · USSt. Louis Children's Hospital · US

Funding

Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Unilateral Hearing Loss in ChildrenK23DC006638 · NIDCD · WASHINGTON UNIVERSITY · PI LIEU, JUDITH EUNKYUNG CHO · 2005 to 2009
$886k
NCRR NIH HHS UL1 RR024992NCRR NIH HHS UL1RR024992NIDCD NIH HHS K23 DC006638NIDCD NIH HHS K23DC006638
6 · The paper itself

Abstract

objectiveTo determine whether children with unilateral hearing loss (UHL) demonstrate worse language skills than their siblings with normal hearing, and whether children with UHL are more likely to receive extra assistance at school. PATIENTS AND

methodsWe conducted a case-control study of 6- to 12-year-old children with UHL compared with sibling controls (74 pairs, n = 148). Scores on the oral portion of the Oral and Written Language Scales (OWLS) were the primary outcome measure. Multivariable analysis was used to determine whether UHL independently predicted OWLS scores after we controlled for potential confounding variables.

resultsChildren with UHL had worse scores than their siblings on language comprehension (91 vs 98; P = .003), oral expression (94 vs 101; P = .007), and oral composite (90 vs 99; P < .001). UHL independently predicted these OWLS scores when multivariable regression was used with moderate effect sizes of 0.3 to 0.7. Family income and maternal education were also independent predictors of oral expression and oral composite scores. No differences were found between children with right- or left-ear UHL or with varying severity of hearing loss. Children with UHL were more likely to have an individualized education plan (odds ratio: 4.4 [95% confidence interval: 2.0-9.5]) and to have received speech-language therapy (odds ratio: 2.6 [95% confidence interval: 1.3-5.4]).

conclusionsSchool-aged children with UHL demonstrated worse oral language scores than did their siblings with normal hearing. These findings suggest that the common practice of withholding hearing-related accommodations from children with UHL should be reconsidered and studied, and that parents and educators should be informed about the deleterious effects of UHL on oral language skills.

Indexed as

Case-Control StudiesChildEducational MeasurementEducational StatusFemaleHearing Loss, UnilateralHumansLanguage DevelopmentLanguage Development DisordersLinear ModelsMaleMultivariate AnalysisPersons with Hearing DisabilitiesSocioeconomic Factors

Identifiers

PMID20457680
PMCPMC3469199
OpenAlexW1998702928

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.