ArticleClinics (Sao Paulo, Brazil)2010
Actinic lesions in fishermen's lower lip: clinical, cytopathological and histopathologic analysis.
Article in Clinics (Sao Paulo, Brazil), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Clinicopathological Analysis of Actinic Cheilitis: A Systematic Review with Meta-analyses.Head and neck pathology · 2023Pooled it
- Overview of oral health status and associated risk factors in maritime settings: An updated systematic review.PloS one · 2023Pooled it
- Mismatch Repair Proteins Immunostaining in Lip Squamous Cell Carcinoma: A Role in Lip Carcinogenesis?Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Evaluation of lip diseases in peddlers on two beaches of Guarujá/Brazil: An observational study.Brazilian dental journal · 2024Observational
- Oral Potentially Malignant Disorders: Etiology, Pathogenesis, and Transformation Into Oral Cancer.Frontiers in pharmacology · 2022Review
- Actinic cheilitis in rural workers: prevalence and associated factors.Einstein (Sao Paulo, Brazil) · 2022Article
- Demographic and Clinicopathologic Features of Actinic Cheilitis and Lip Squamous Cell Carcinoma: a Brazilian Multicentre Study.Head and neck pathology · 2020Article
- Fludroxycortide cream as an alternative therapy for actinic cheilitis.Clinical oral investigations · 2019Article
- Actinic cheilitis and lip squamous cell carcinoma: Literature review and new data from Brazil.Journal of clinical and experimental dentistry · 2019Review
- Non-invasive imaging of actinic cheilitis and squamous cell carcinoma of the lip.Molecular and clinical oncology · 2018Article
- Diclofenac sodium gel therapy as an alternative to actinic cheilitis.Clinical oral investigations · 2018Article
- Clinicopathological profile and management of 161 cases of actinic cheilitis.Anais brasileiros de dermatologiaObservational
- Link between immunoexpression of hMLH1 and hMSH2 proteins and clinical-epidemiological aspects of actinic cheilitis.Anais brasileiros de dermatologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionActinic cheilitis (AC) is considered to be a pre-malignant lesion or an incipient and superficial form of lip squamous cell carcinoma. It is commonly found in individuals whose occupational activities are related to chronic sun exposure and the definitive diagnosis is performed with biopsy. Although Exfoliative cytology has been used as a screening procedure to evaluate cancer of the oral cavity no studies have proposed the use of exfoliative cytologic analysis to evaluate and diagnose AC.
objectiveThe purpose of this study was to evaluate lower lip lesions on fishermen related to chronic solar exposure using clinical, cytologic and histopathologic analyses. PATIENTS AND
methodsSmears taken from the vermilion of the lower lips of 125 fishermen and 30 control individuals were subjected to cytologic analysis.
resultsThe harvested cells were sufficient for cytologic analysis in 83.2% of the samples. Sixteen fishermen exhibited prominent lower lip lesions that justified biopsy and histological studies. In total, 4 specimens were malignant (3.2%), and 12 displayed epithelial dysplasia, demonstrating that the prevalence of epithelial dysplasia and malignant lesions was high among the fishermen population. These conditions were strongly associated with infiltration and blurring of the vermilion margin of the lower lip.
conclusionThe cytologic analysis was not useful for detecting epithelial dysplasia or malignant alterations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.