ArticleNature cell biology2010
alpha-catenin mechanosensing for adherens junctions.
Article in Nature cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Mechanical control in dental and jaw morphogenesis and remodeling.International journal of oral science · 2026Review
- Nonmuscle myosin IIA (NMIIA) regulates anisotropic cell tension to maintain the hexagonal packing of mouse lens meridional row cells.Molecular biology of the cell · 2025Article
- A Simple Method to Test Mechanical Strain on Epithelial Cell Monolayers Using a 3D-Printed Stretcher.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Intercellular Adhesion Stiffness Moderates Cell Decoupling as a Function of Substrate Stiffness.Biophysical journal · 2020Article
- Tissue Mechanical Forces and Evolutionary Developmental Changes Act Through Space and Time to Shape Tooth Morphology and Function.BioEssays : news and reviews in molecular, cellular and developmental biology · 2018Review
- Epidermal growth factor receptor and integrins control force-dependent vinculin recruitment to E-cadherin junctions.Journal of cell science · 2018Article
- α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart.Development (Cambridge, England) · 2018Article
- Biophysical Tools to Study Cellular Mechanotransduction.Bioengineering (Basel, Switzerland) · 2017Review
- Mechano-adaptive sensory mechanism of α-catenin under tension.Scientific reports · 2016Article
- Inter-cellular exchange of cellular components via VE-cadherin-dependent trans-endocytosis.PloS one · 2014Article
- Dimer asymmetry defines α-catenin interactions.Nature structural & molecular biology · 2013Article
- Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling.Progress in molecular biology and translational science · 2013Review
- The cytoskeletal protein α-catenin unfurls upon binding to vinculin.The Journal of biological chemistry · 2012Article
- Crossroads of integrins and cadherins in epithelia and stroma remodeling.Cell adhesion & migrationReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The balance of cohesion and remodelling is essential for the integrity and morphogenesis of epithelia. This requires adhesion and transmission of actomyosin tension, both of which are mediated by E-cadherin. The finding that actomyosin tension reinforces mechanical coupling of actin to E-cadherin through alpha-catenin reveals similarities with integrin regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.