Evidence map›Paper›PMID 20453170›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2010

Vascular potential of human pluripotent stem cells.

Ionela Iacobas, Archana Vats, Karen K Hirschi

Open access · bronzeAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Vascular precursor cells.Genes & cancer · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ionela IacobasDepartment of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Archana Vats
Karen K Hirschi
Baylor College of Medicine · US

Funding

Tissue Engineering of Hematopoietic BoneR01EB005173 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI HIRSCHI, KAREN KEMPER · 2005 to 2009
$5.9M
Neuro-Vascular RegenerationP20EB007076 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI HIRSCHI, KAREN KEMPER · 2006 to 2009
$4.4M
Role of Gap Junctions in Blood Vessel AssemblyR01HL077675 · NHLBI · YALE UNIVERSITY · PI BURT, JANIS M, HIRSCHI, KAREN KEMPER · 2004 to 2012
$2.7M
Human Endothelial Cell DifferentiationR01HL096360 · NHLBI · YALE UNIVERSITY · PI HIRSCHI, KAREN KEMPER · 2009 to 2013
$1.5M
NHLBI NIH HHS R01 HL077675NHLBI NIH HHS R01 HL096360NIBIB NIH HHS P20 EB007076NIBIB NIH HHS R01 EB005173
6 · The paper itself

Abstract

Cardiovascular disease is the number one cause of death and disability in the US. Understanding the biological activity of stem and progenitor cells, and their ability to contribute to the repair, regeneration and remodeling of the heart and blood vessels affected by pathological processes is an essential part of the paradigm in enabling us to achieve a reduction in related deaths. Both human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are promising sources of cells for clinical cardiovascular therapies. Additional in vitro studies are needed, however, to understand their relative phenotypes and molecular regulation toward cardiovascular cell fates. Further studies in translational animal models are also needed to gain insights into the potential and function of both human ES- and iPS-derived cardiovascular cells, and enable translation from experimental and preclinical studies to human trials.

Indexed as

Neovascularization, PhysiologicAnimalsBlood VesselsCardiovascular DiseasesCell DifferentiationCell ProliferationEmbryonic Stem CellsHumansInduced Pluripotent Stem CellsPhenotypePluripotent Stem CellsSignal TransductionStem Cell Niche

Identifiers

PMID20453170
PMCPMC2896478
OpenAlexW2073635697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.