ArticleApplied and environmental microbiology2010
Characterization of the NifA-RpoN regulon in Rhizobium etli in free life and in symbiosis with Phaseolus vulgaris.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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34 citing papers in PubMed, 67 citations in OpenAlex.
- A Bradyrhizobium isolate from a marine diatom induces nitrogen-fixing nodules in a terrestrial legume.Nature microbiology · 2025Article
- Identification and characterization of the TetR family transcriptional regulator NffT inApplied and environmental microbiology · 2024Article
- Rice N-biofertilization by inoculation with an engineered photosynthetic diazotroph.World journal of microbiology & biotechnology · 2024Article
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- Purification and Biochemical Characterization of the DNA Binding Domain of the Nitrogenase Transcriptional Activator NifA from Gluconacetobacter diazotrophicus.The protein journal · 2023Article
- Exploring the cellular surface polysaccharide and root nodule symbiosis characteristics of theMicrobiology spectrum · 2023Article
- Review
- Role of two RpoN inFrontiers in microbiology · 2023Article
- Production of the plant hormone gibberellin by rhizobia increases host legume nodule size.The ISME journal · 2022Article
- Article
- Metabolomics and Dual RNA-Sequencing on Root Nodules Revealed New Cellular Functions Controlled byMetabolites · 2021Article
- Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis.PLoS genetics · 2021Article
- Effectiveness of nitrogen fixation in rhizobia.Microbial biotechnology · 2020Review
- Principal component analysis on LC‑MS/MS and 2DE‑MALDI‑TOF in glioblastoma cell lines reveals that mitochondria act as organelle sensors of the metabolic state in glioblastoma.Oncology reports · 2020Article
- Article
- Analysis of differentially upregulated proteins in ptsHIcrrApplied microbiology and biotechnology · 2018Article
- The ropAe gene encodes a porin-like protein involved in copper transit in Rhizobium etli CFN42.MicrobiologyOpen · 2018Article
- Functional Genomics Approaches to Studying Symbioses between Legumes and Nitrogen-Fixing Rhizobia.High-throughput · 2018Review
- Metabolomics and Transcriptomics Identify Multiple Downstream Targets of Paraburkholderia phymatum σInternational journal of molecular sciences · 2018Article
- Characterization of CYP115 As a Gibberellin 3-Oxidase Indicates That Certain Rhizobia Can Produce Bioactive Gibberellin AACS chemical biology · 2017Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The NifA-RpoN complex is a master regulator of the nitrogen fixation genes in alphaproteobacteria. Based on the complete Rhizobium etli genome sequence, we constructed an R. etli CFN42 oligonucleotide (70-mer) microarray and utilized this tool, reverse transcription (RT)-PCR analysis (transcriptomics), proteomics, and bioinformatics to decipher the NifA-RpoN regulon under microaerobic conditions (free life) and in symbiosis with bean plants. The R. etli NifA-RpoN regulon was determined to contain 78 genes, including the genes involved in nitrogen fixation, and the analyses revealed 42 new NifA-RpoN-dependent genes. More importantly, this study demonstrated that the NifA-RpoN regulon is composed of genes and proteins that have very diverse functions, that play fundamental and previously less appreciated roles in regulating the normal physiology of the cell, and that have important functions in providing adequate conditions for efficient nitrogen fixation in symbiosis. The R. etli NifA-RpoN regulon defined here has some components in common with other NifA-RpoN regulons described previously, but the vast majority of the components have been found only in the R. etli regulon, suggesting that they have a specific role in this bacterium and particular requirements during nitrogen fixation compared with other symbiotic bacterial models.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.