ArticleExperimental gerontology2010
The impact of larval and adult dietary restriction on lifespan, reproduction and growth in the mosquito Aedes aegypti.
Article in Experimental gerontology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.
- Effects of desiccation stress on adult female longevity in Aedes aegypti and Ae. albopictus (Diptera: Culicidae): results of a systematic review and pooled survival analysis.Parasites & vectors · 2018Pooled it
- From fertilizer to insecticide: urban leaf litter chemistry alters the survival landscape of Aedes aegypti.Pest management science · 2026Article
- The microbiota impacts life history traits and mating success in malebioRxiv : the preprint server for biology · 2026Article
- Effects of Yeast on the Growth and Development ofInsects · 2025Article
- Physical and chemical characteristics of Aedes larval habitats in Metema District, Northwest, Ethiopia.BMC ecology and evolution · 2025Article
- Variation in diet concentration and bacterial inoculum size in larval habitats shapes the performance of the Asian tiger mosquito, Aedes albopictus.Microbiome · 2025Article
- Optimizing larval mass-rearing techniques for Aedes mosquitoes: enhancing production and quality for genetic control strategies.Parasite (Paris, France) · 2025Article
- Genomic Analysis ofVector borne and zoonotic diseases (Larchmont, N.Y.) · 2024Article
- Larval diet and temperature alter mosquito immunity and development: using body size and developmental traits to track carry-over effects on longevity.Parasites & vectors · 2023Article
- The mosquito Aedes aegypti requires a gut microbiota for normal fecundity, longevity and vector competence.Communications biology · 2023Article
- Nutritional stress compromises mosquito fitness and antiviral immunity, while enhancing dengue virus infection susceptibility.Communications biology · 2023Article
- The influence of the larval microbiome on susceptibility to Zika virus is mosquito genotype-dependent.PLoS pathogens · 2023Article
- Effect of larval diets on the life table parameters of dengue mosquito, Aedes aegypti (L.) (Diptera: Culicidae) using age-stage two sex life table theory.Scientific reports · 2023Article
- Batch RearingCold Spring Harbor protocols · 2023Article
- MosChito rafts as effective and eco-friendly tool for the delivery of a Bacillus thuringiensis-based insecticide to Aedes albopictus larvae.Scientific reports · 2023Article
- TargetingViruses · 2023Review
- Using body size as an indicator for age structure in field populations of Aedes aegypti (Diptera: Culicidae).Parasites & vectors · 2022Article
- Human age reversal: Fact or fiction?Aging cell · 2022Review
- Differential effects of larval and adult nutrition on female survival, fecundity, and size of the yellow fever mosquito, Aedes aegypti.Frontiers in zoology · 2021Article
- Size as a Proxy for Survival in Aedes aegypti (Diptera: Culicidae) Mosquitoes.Journal of medical entomology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Dietary restriction extends lifespan in many organisms, but little is known about how it affects hematophagous arthropods. We demonstrated that diet restriction during either larval or adult stages extends Aedes aegypti lifespan. A. aegypti females fed either single or no blood meals survived 30-40% longer than those given weekly blood meals. However, mosquitoes given weekly blood meals produced far more eggs. To minimize reproduction's impact on lifespan, adult mosquitoes were fed artificial blood meals containing <10% of the protein in normal human blood, minimizing egg production. A. aegypti fed artificial blood meals containing 25mg/ml of BSA had significantly shorter lifespans than those fed either 10 or 5mg/ml. To assess the impact of larval dietary restriction on adult lifespan, we maintained larval A. aegypti on 2X, 1X (normal diet), 0.5X or 0.25X diets. Adult mosquitoes fed 0.5X and 0.25X larval diets survived significantly longer than those fed the 2X larval diet regardless of adult diet. In summary, dietary restriction during both larval and adult stages extends lifespan. This diet-mediated lifespan extension has important consequences for understanding how dietary restriction regulates lifespan and disease transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.