Evidence map›Paper›PMID 20451408›Full record

ReviewSeminars in immunology2010

gammadelta T cell subsets: a link between TCR and function?

Rebecca L O'Brien, Willi K Born

Abstract readReview
In one paragraph

Review in Seminars in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The roles of immune cells in Behçet's disease.Advances in rheumatology (London, England) · 2023
    Review
  5. Article
  6. Development of γδ T Cells: Soldiers on the Front Lines of Immune Battles.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. T-cell frequencies of CD8Bone marrow transplantation · 2019
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017
    Article
  18. IL-17Nature immunology · 2017
    Review
  19. Dermal VγAmerican journal of translational research · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rebecca L O'BrienIntegrated Dept. of Immunology, National Jewish Health, 1400 Jackson St., Denver, CO 80206, United States; Univ. of Colorado Denver, Aurora, CO 80045, USA. obrienr@njhealth.org
Willi K Born

Funding

The Basis of Functional Variation in Gamma/Delta T cellsR01AI044920 · NIAID · NATIONAL JEWISH HEALTH · PI O'BRIEN, REBECCA L. · 1999 to 2009
$3.0M
NIAID NIH HHS R01 AI044920
6 · The paper itself

Abstract

The gammadelta T lmphocytes are often divided into subsets based upon expression of certain TCR components. This division was initially made because gammadelta T cells residing in particular epithelia were found to show tissue specific differences in their TCRs. Many examples now show that gammadelta T cell subsets also appear to be biased to carry out particular functions. This suggests that particular gammadelta TCR types direct the cells to acquire a certain type of functional programming during thymic development. Here, we describe functionally distinct, TCR-defined gammadelta T cell subsets, and evidence that their functions are predetermined in the thymus.

Indexed as

AnimalsCell DifferentiationHumansReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, gamma-deltaThymus GlandT-Lymphocyte SubsetsReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID20451408
PMCPMC2906689

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.