Evidence map›Paper›PMID 20450352›Full record

ReviewAnnual review of biomedical engineering2010

Mechanisms of defibrillation.

Derek J Dosdall, Vladimir G Fast, Raymond E Ideker

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Simultaneous optical imaging of gastric slow waves and contractions in the in vivo porcine stomach.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  6. Article
  7. Article
  8. Terminating spiral waves with a single designed stimulus: Teleportation as the mechanism for defibrillation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. [Recent advances in external cardiac defibrillation techniques].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020
    Review
  14. Gene therapy for inherited arrhythmias.Cardiovascular research · 2020
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Derek J DosdallDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA. djd@crml.uab.edu
Vladimir G Fast
Raymond E Ideker

Funding

Mechanisms of Long Duration Fibrillation, Defibrillation and RefibrillationR01HL085370 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI IDEKER, RAYMOND E. · 2007 to 2014
$2.9M
CARDIAC MAPPING OF VENTRICULAR DEFIBRILLATIONR01HL042760 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI IDEKER, RAYMOND E. · 1989 to 2006
$2.3M
Mechanisms of Defibrillation &Shock-Induced ArrhythmiasR01HL067748 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FAST, VLADIMIR G · 2001 to 2012
$2.1M
Role of the Purkinje System in Long Duration Ventricular FibrillationR00HL091138 · NHLBI · UNIVERSITY OF UTAH · PI DOSDALL, DEREK J · 2010 to 2013
$735k
Role of the Purkinje System in Long Duration Ventricular FibrillationK99HL091138 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DOSDALL, DEREK J · 2009 to 2010
$212k
NHLBI NIH HHS HL42760NHLBI NIH HHS HL67748NHLBI NIH HHS HL85370NHLBI NIH HHS K99 HL091138NHLBI NIH HHS K99HL091138NHLBI NIH HHS L30 HL082315NHLBI NIH HHS R00 HL091138NHLBI NIH HHS R01 HL042760NHLBI NIH HHS R01 HL067748NHLBI NIH HHS R01 HL085370
6 · The paper itself

Abstract

Electrical shock has been the one effective treatment for ventricular fibrillation for several decades. With the advancement of electrical and optical mapping techniques, histology, and computer modeling, the mechanisms responsible for defibrillation are now coming to light. In this review, we discuss recent work that demonstrates the various mechanisms responsible for defibrillation. On the cellular level, membrane depolarization and electroporation affect defibrillation outcome. Cell bundles and collagenous septae are secondary sources and cause virtual electrodes at sites far from shocking electrodes. On the whole-heart level, shock field gradient and critical points determine whether a shock is successful or whether reentry causes initiation and continuation of fibrillation.

Indexed as

Electric CountershockAnimalsArrhythmias, CardiacDogsElectrodesElectroporationHeartHumansModels, CardiovascularRabbitsSwineVentricular Fibrillation

Identifiers

PMID20450352
PMCPMC3984906

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.