SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2010
A systematic review of dental disease in patients undergoing cancer therapy.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
115 citing papers in PubMed, 7 syntheses or guidelines pooled it, 309 citations in OpenAlex.
- A systematic review of dentists' knowledge, perception, practice and confidence in managing patients with cancers.BMC health services research · 2024Pooled it
- Prevalence of oral diseases in patients under palliative care: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Effectiveness of glass ionomer cements in the restorative treatment of radiation-related caries - a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- The impact of head and neck radiotherapy on the dentine-enamel junction: a systematic review.Medicina oral, patologia oral y cirugia bucal · 2020Pooled it
- A systematic review of dental disease management in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Pooled it
- The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana-Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline.The oncologist · 2017Guideline
- A systematic review of dental late effects in survivors of childhood cancer.Pediatric blood & cancer · 2014Pooled it
- A randomized controlled trial comparing the effect of salivary substitute and fluoride varnish on radiation caries in irradiated head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Push-out bond strength of fiber posts to irradiated and non-irradiated intraradicular dentin.Clinical oral investigations · 2022Trial
- Results of a randomized controlled phase III trial: efficacy of polyphenol-containing cystus® tea mouthwash solution for the reduction of mucositis in head and neck cancer patients undergoing external beam radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021Trial
- International field testing of the psychometric properties of an EORTC quality of life module for oral health: the EORTC QLQ-OH15.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Trial
- Anti-caries effect of CPP-ACP in irradiated nasopharyngeal carcinoma patients.Clinical oral investigations · 2015Trial
- Sicca symptoms and their impact on quality of life among very long-term survivors after hematopoietic SCT.Bone marrow transplantation · 2013Trial
- Oral health in cancer patients: results of a monocentric survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Associations Between Systemic Diseases and Dental Pulp Diagnoses: A Retrospective Chart Study Using a Locally Deployed Large Language Model.Dentistry journal · 2026Article
- Early effects of X-ray irradiation on rat incisor periodontal ligament morphology and MMP-2 expression.Journal of molecular histology · 2026Article
- Oral disease burden in children and adolescents scheduled for allogeneic haematopoietic stem cell transplantation: a multicentre study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Longitudinal periodontal deterioration and salivary dysfunction following head and neck radiotherapy: a prospective multicenter cohort study.Odontology · 2026Article
- Proactive preventive dental care to maintain eating function in palliative care: a narrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Review
- Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis purpose of this systematic review was to evaluate the literature and update our current understanding of the impact of present cancer therapies on the dental apparatus (teeth and periodontium) since the 1989 NIH Development Consensus Conference on the Oral Complications of Cancer Therapies. REVIEW
methodA systematic literature search was conducted with assistance from a research librarian in the databases MEDLINE/PubMed and EMBASE for articles published between 1 January 1990 and 31 December 2008. Each study was independently assessed by two reviewers. Taking into account predetermined quality measures, a weighted prevalence was calculated for the prevalence of dental caries, severe gingival disease, and dental infection. Data on DMFT/dmft, DMFS/dmfs, plaque, and gingival indexes were also gathered. The level of evidence, recommendation, and guideline (if possible) were given for published preventive and management strategies.
resultsSixty-four published papers between 1990 and 2008 were reviewed. The weighted overall prevalence of dental caries was 28.1%. The overall DMFT for patients who were post-antineoplastic therapy was 9.19 (SD, 7.98; n = 457). The overall plaque index for patients who were post-antineoplastic therapy was 1.38 (SD, 0.25; n = 189). The GI for patients who were post-chemotherapy was 1.02 (SD, 0.15; n = 162). The weighted prevalence of dental infections/abscess during chemotherapy was reported in three studies and was 5.8%.
conclusionsPatients who were post-radiotherapy had the highest DMFT. The use of fluoride products and chlorhexidine rinses are beneficial in patients who are post-radiotherapy. There continues to be lack of clinical studies on the extent and severity of dental disease that are associated with infectious complications during cancer therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.