Evidence map›Paper›PMID 20448959›Full record

ArticleChemical communications (Cambridge, England)2009

Silica nanoparticle supported lipid bilayers for gene delivery.

Juewen Liu, Alison Stace-Naughton, C Jeffrey Brinker

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
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  8. Biomimetic particles as therapeutics.Trends in biotechnology · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Juewen LiuCenter for Micro-Engineered Materials, University of New Mexico, Albuquerque, NM, USA.
Alison Stace-Naughton
C Jeffrey Brinker
University of New Mexico · USSandia National Laboratories · US

Funding

NATIONAL CENTER FOR DESIGN:BIOMIMETIC NANOCONDUCTOR(RMI)PN2EY016570 · NEI · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI JAKOBSSON, ERIC G · 2005 to 2009
$6.6M
NEI NIH HHS PN2 EY016570
6 · The paper itself

Abstract

Silica nanoparticle supported cationic lipids can effectively bind plasmid DNAs and transfect mammalian cells with an efficiency that depends on both the particle size and lipid composition; here the gene delivery and expression process has been confirmed by confocal fluorescence microscopy.

Indexed as

Gene Transfer TechniquesAnimalsCHO CellsCricetinaeCricetulusDNALipid BilayersMicroscopy, FluorescenceNanoparticlesParticle SizePlasmidsSilicon DioxideTransfectionDNALipid BilayersSilicon Dioxide

Identifiers

PMID20448959
PMCPMC2867086
OpenAlexW1974144082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.