ArticleMolecular plant pathology2010
The two-component histidine kinase Fhk1 controls stress adaptation and virulence of Fusarium oxysporum.
Article in Molecular plant pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 64 citations in OpenAlex.
- The Ubiquitous Wilt-Inducing PathogenPathogens (Basel, Switzerland) · 2024Review
- Induced Expression ofMicroorganisms · 2023Article
- Post-translational modifications drive secondary metabolite biosynthesis in Aspergillus: a review.Environmental microbiology · 2022Review
- Unveiling the Role Displayed byJournal of fungi (Basel, Switzerland) · 2021Article
- Distinct role of HAMP and HAMP-like linker domains in regulating the activity of Hik1p, a hybrid histidine kinase 3 from Magnaporthe oryzae.Molecular genetics and genomics : MGG · 2021Article
- Contribution of NADPH-cytochrome P450 Reductase to Azole Resistance inFrontiers in microbiology · 2021Article
- Proteome-Wide Analysis of Lysine 2-Hydroxyisobutyrylated Proteins inFrontiers in microbiology · 2021Article
- FocSge1 in Fusarium oxysporum f. sp. cubense race 1 is essential for full virulence.BMC microbiology · 2020Article
- Genome sequence and spore germination-associated transcriptome analysis of Corynespora cassiicola from cucumber.BMC microbiology · 2020Article
- Analysis of reference genes stability and histidine kinase expression under cold stress in Cordyceps militaris.PloS one · 2020Article
- Overexpression of the CORVET complex alleviates the fungicidal effects of fludioxonil on the yeastThe Journal of biological chemistry · 2019Article
- Three Fusarium oxysporum mitogen-activated protein kinases (MAPKs) have distinct and complementary roles in stress adaptation and cross-kingdom pathogenicity.Molecular plant pathology · 2017Article
- Spontaneous and CRISPR/Cas9-induced mutation of the osmosensor histidine kinase of the canola pathogenFungal biology and biotechnology · 2017Article
- Fungal Histidine Phosphotransferase Plays a Crucial Role in Photomorphogenesis and Pathogenesis inFrontiers in chemistry · 2017Article
- Plant Defensins NaD1 and NaD2 Induce Different Stress Response Pathways in Fungi.International journal of molecular sciences · 2016Article
- Dissecting the role of histidine kinase and HOG1 mitogen-activated protein kinase signalling in stress tolerance and pathogenicity of Parastagonospora nodorum on wheat.Microbiology (Reading, England) · 2016Article
- CCR4-Not Complex Subunit Not2 Plays Critical Roles in Vegetative Growth, Conidiation and Virulence in Watermelon Fusarium Wilt PathogenFrontiers in microbiology · 2016Article
- Genome and transcriptome analysis of the fungal pathogen Fusarium oxysporum f. sp. cubense causing banana vascular wilt disease.PloS one · 2014Article
- Expression analysis reveals a role for hydrophobic or epicuticular wax signals in pre-penetration structure formation of Phakopsora pachyrhizi.Plant signaling & behavior · 2013Article
- A two-component histidine kinase Shk1 controls stress response, sclerotial formation and fungicide resistance in Sclerotinia sclerotiorum.Molecular plant pathology · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Fungal histidine kinases (HKs) have been implicated in different processes, such as the osmostress response, hyphal development, sensitivity to fungicides and virulence. Members of HK class III are known to signal through the HOG mitogen-activated protein kinase (MAPK), but possible interactions with other MAPKs have not been explored. In this study, we have characterized fhk1, encoding a putative class III HK from the soil-borne vascular wilt pathogen Fusarium oxysporum. Inactivation of fhk1 resulted in resistance to phenylpyrrole and dicarboximide fungicides, as well as increased sensitivity to hyperosmotic stress and menadione-induced oxidative stress. The osmosensitivity of Delta fhk1 mutants was associated with a striking and previously unreported change in colony morphology. The Delta fhk1 strains showed a significant decrease in virulence on tomato plants. Epistatic analysis between Fhk1 and the Fmk1 MAPK cascade indicated that Fhk1 does not function upstream of Fmk1, but that the two pathways may interact to control the response to menadione-induced oxidative stress.
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