ArticleProceedings of the National Academy of Sciences of the United States of America2010
Colloquium paper: gene-culture coevolution in the age of genomics.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 380 citations in OpenAlex.
- Genomic approaches for understanding the evolution of the human brain.Nature neuroscience · 2026Review
- Social information creates self-fulfilling prophecies in judgments of pain, vicarious pain, and cognitive effort.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Not by Selection Alone: Expanding the Scope of Gene-Culture Coevolution.Evolutionary anthropology · 2025Review
- An empirically-based scenario for the evolution of cultural transmission in the human lineage during the last 3.3 million years.PloS one · 2025Article
- Signatures of selection with cultural interference.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Half a century of quantitative cultural evolution.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- 3.3 million years of stone tool complexity suggests that cumulative culture began during the Middle Pleistocene.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Human social genomics: Concepts, mechanisms, and implications for health.Lifestyle medicine (Hoboken, N.J.) · 2023Article
- Steps to individuality in biology and culture.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Conceptual and methodological issues in the study of the personality-and-culture relationship.Frontiers in psychology · 2023Article
- One Health Requires a Theory of Agency.Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees · 2022Article
- Article
- 1,000 ancient genomes uncover 10,000 years of natural selection in Europe.bioRxiv : the preprint server for biology · 2022Article
- Direct reciprocity between individuals that use different strategy spaces.PLoS computational biology · 2022Article
- The Interaction Effect of Parental Rejection and Oxytocin Receptor Gene Polymorphism on Depression: A Cross-Cultural Study in Non-Clinical Samples.International journal of environmental research and public health · 2022Article
- Exploring gene-culture coevolution in humans by inferring neuroendophenotypes: A case study of the oxytocin receptor gene and cultural tightness.Genes, brain, and behavior · 2022Article
- Vocal learning as a preadaptation for the evolution of human beat perception and synchronization.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Ethnic Identity and Genome Wide Runs of Homozygosity.Behavior genetics · 2021Article
- Long-term gene-culture coevolution and the human evolutionary transition.Proceedings. Biological sciences · 2021Review
- The Role of the Learner in the Cultural Evolution of Vocalizations.Frontiers in psychology · 2021Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of socially learned information (culture) is central to human adaptations. We investigate the hypothesis that the process of cultural evolution has played an active, leading role in the evolution of genes. Culture normally evolves more rapidly than genes, creating novel environments that expose genes to new selective pressures. Many human genes that have been shown to be under recent or current selection are changing as a result of new environments created by cultural innovations. Some changed in response to the development of agricultural subsistence systems in the Early and Middle Holocene. Alleles coding for adaptations to diets rich in plant starch (e.g., amylase copy number) and to epidemic diseases evolved as human populations expanded (e.g., sickle cell and G6PD deficiency alleles that provide protection against malaria). Large-scale scans using patterns of linkage disequilibrium to detect recent selection suggest that many more genes evolved in response to agriculture. Genetic change in response to the novel social environment of contemporary modern societies is also likely to be occurring. The functional effects of most of the alleles under selection during the last 10,000 years are currently unknown. Also unknown is the role of paleoenvironmental change in regulating the tempo of hominin evolution. Although the full extent of culture-driven gene-culture coevolution is thus far unknown for the deeper history of the human lineage, theory and some evidence suggest that such effects were profound. Genomic methods promise to have a major impact on our understanding of gene-culture coevolution over the span of hominin evolutionary history.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.