ArticleJournal of neurophysiology2010
Subthreshold membrane conductances enhance directional selectivity in vertebrate sensory neurons.
Article in Journal of neurophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations.iScience · 2025Article
- Electrosensory midbrain neurons optimally decode ascending input during object localization.The Journal of physiology · 2025Article
- Population Coding of Natural Electrosensory Stimuli by Midbrain Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neuronal On- and Off-type heterogeneities improve population coding of envelope signals in the presence of stimulus-induced noise.Scientific reports · 2020Article
- Neural Synchrony Gives Rise to Amplitude- and Duration-Invariant Encoding Consistent With Perception of Natural Communication Stimuli.Frontiers in neuroscience · 2020Article
- Serotonergic Modulation of Sensory Neuron Activity and Behavior inFrontiers in integrative neuroscience · 2020Article
- Descending pathways generate perception of and neural responses to weak sensory input.PLoS biology · 2018Article
- Motion parallax in electric sensing.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Adaptation to second order stimulus features by electrosensory neurons causes ambiguity.Scientific reports · 2016Article
- Neural correlations enable invariant coding and perception of natural stimuli in weakly electric fish.eLife · 2016Article
- Weak signal amplification and detection by higher-order sensory neurons.Journal of neurophysiology · 2016Article
- Burst Firing in the Electrosensory System of Gymnotiform Weakly Electric Fish: Mechanisms and Functional Roles.Frontiers in computational neuroscience · 2016Review
- Parallel sparse and dense information coding streams in the electrosensory midbrain.Neuroscience letters · 2015Article
- Electrosensory Midbrain Neurons Display Feature Invariant Responses to Natural Communication Stimuli.PLoS computational biology · 2015Article
- Motion processing across multiple topographic maps in the electrosensory system.Physiological reports · 2014Article
- Parallel coding of first- and second-order stimulus attributes by midbrain electrosensory neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Direction selectivity in the larval zebrafish tectum is mediated by asymmetric inhibition.Frontiers in neural circuits · 2012Article
- Bursts and isolated spikes code for opposite movement directions in midbrain electrosensory neurons.PloS one · 2012Article
- Sparse and dense coding of natural stimuli by distinct midbrain neuron subpopulations in weakly electric fish.Journal of neurophysiology · 2011Article
- A diversity of synaptic filters are created by temporal summation of excitation and inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
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Authors and funding
2 authors.
Funding
Abstract
Directional selectivity, in which neurons respond preferentially to one "preferred" direction of movement over the opposite "null" direction, is a critical computation that is found in the central nervous systems of many animals. Such responses are generated using two mechanisms: spatiotemporal convergence via pathways that differ in the timing of information from different locations on the receptor array and the nonlinear integration of this information. Previous studies have showed that various mechanisms may act as nonlinear integrators by suppressing the response in the null direction. Here we show, through a combination of mathematical modeling and in vivo intracellular recordings, that subthreshold membrane conductances can act as a nonlinear integrator by increasing the response in the preferred direction of motion only, thereby enhancing the directional bias. Such subthreshold conductances are ubiquitous in the CNS and therefore may be used in a wide array of computations that involve the enhancement of an existing bias arising from differential spatiotemporal filtering.
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