Evidence map›Paper›PMID 20444716›Full record

ArticleProceedings. Biological sciences2010

Condition, innate immunity and disease mortality of inbred crows.

Andrea K Townsend, Anne B Clark, Kevin J McGowan, Andrew D Miller, Elizabeth L Buckles

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Maternal Androgens in Dominant Meerkats (Ecology and evolution · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Genetic diversity, inbreeding and cancer.Proceedings. Biological sciences · 2018
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Ecophysiology of avian migration in the face of current global hazards.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2012
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrea K TownsendFuller Evolutionary Biology Program, Cornell Laboratory of Ornithology, , 159 Sapsucker Woods Road, Ithaca, NY 14850, USA. at256@cornell.edu
Anne B Clark
Kevin J McGowan
Andrew D Miller
Elizabeth L Buckles
Cornell University · USBinghamton University · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cooperatively breeding American crows (Corvus brachyrhynchos) suffer a severe disease-mediated survival cost from inbreeding, but the proximate mechanisms linking inbreeding to disease are unknown. Here, we examine indices of nestling body condition and innate immunocompetence in relationship to inbreeding and disease mortality. Using an estimate of microsatellite heterozygosity that predicts inbreeding in this population, we show that inbred crows were in relatively poor condition as nestlings, and that body condition index measured in the first 2-33 days after hatching, in addition to inbreeding index, predicted disease probability in the first 34 months of life. Inbred nestlings also mounted a weaker response along one axis of innate immunity: the proportion of bacteria killed in a microbiocidal assay increased as heterozygosity index increased. Relatively poor body condition and low innate immunocompetence are two mechanisms that might predispose inbred crows to ultimate disease mortality. A better understanding of condition-mediated inbreeding depression can guide efforts to minimize disease costs of inbreeding in small populations.

Indexed as

InbreedingAnimalsBird DiseasesCrowsEscherichia coli InfectionsFemaleImmunity, InnateImmunocompetenceMaleMicrosatellite RepeatsNesting BehaviorPopulation DynamicsSexual Behavior, Animal

Identifiers

PMID20444716
PMCPMC2981987
OpenAlexW2131543112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.