ReviewEnvironmental health perspectives2010
A review of pesticide exposure and cancer incidence in the Agricultural Health Study cohort.
Review in Environmental health perspectives, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 242 citations in OpenAlex.
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review.Ecotoxicology and environmental safety · 2021Pooled it
- Systematic review and meta-analysis of glyphosate exposure and risk of lymphohematopoietic cancers.Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes · 2016Pooled it
- Prostate cancer and toxicity from critical use exemptions of methyl bromide: environmental protection helps protect against human health risks.Environmental health : a global access science source · 2012Pooled it
- Dietary and Lifestyle Patterns among Young Patients with Lung Cancer: Analysis of Mutation-Specific Phenotypes.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Article
- Research Trends on Pesticide Exposure and Cancer Development: A Global Literature Review (2005-2024).International journal of environmental research and public health · 2026Review
- Exceptional use: examining methyl bromide applications in California 2016-2022.Environmental research communications · 2026Article
- Integrating epidemiological and bioinformatics analyses identified the effects of organophosphate pesticides accelerating biological aging.International journal of surgery (London, England) · 2025Article
- Expected effects of a global transformation of agricultural pest management.Nature communications · 2025Article
- Impact of pesticide diazinon on gastric cancer cell lines and the alteration of cholinergic and serotonergic pathway genes affecting cell proliferation.Scientific reports · 2025Article
- An Analysis of Male Breast Cancer Incidence, Mortality, and Disease Burden Among Commonwealth Countries.Cureus · 2025Article
- Role ofMicroorganisms · 2025Article
- Pesticide pollution in India: Environmental and health risks, and policy challenges.Toxicology reports · 2024Article
- Delineating Urbanicity and Rurality: Impact on Environmental Exposure Assessment.Environmental science & technology · 2024Article
- Review
- Review
- Determination of genotoxic damages of picloram and dicamba with comet assay in Allium cepa rooted in tissue culture and distilled water.Molecular biology reports · 2022Article
- Exocrine pancreatic cancer and living near to waste sites containing hazardous organic chemicals, New York State, USA - an 18-year population-based study.International journal of occupational medicine and environmental health · 2022Article
- Cancer Epidemiology in Hispanic Populations: What Have We Learned and Where Do We Need to Make Progress?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Review
- Situations of work-related diseases and injuries among agriculturists in the upper northeast regions of Thailand.F1000Research · 2022Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe reviewed epidemiologic evidence related to occupational pesticide exposures and cancer incidence in the Agricultural Health Study (AHS) cohort. DATA SOURCES: Studies were identified from the AHS publication list available at http://aghealth.nci.nih.gov as well as through a Medline/PubMed database search in March 2009. We also examined citation lists. Findings related to lifetime-days and/or intensity-weighted lifetime-days of pesticide use are the primary focus of this review, because these measures allow for the evaluation of potential exposure-response relationships. DATA SYNTHESIS: We reviewed 28 studies; most of the 32 pesticides examined were not strongly associated with cancer incidence in pesticide applicators. Increased rate ratios (or odds ratios) and positive exposure-response patterns were reported for 12 pesticides currently registered in Canada and/or the United States (alachlor, aldicarb, carbaryl, chlorpyrifos, diazinon, dicamba, S-ethyl-N,N-dipropylthiocarbamate, imazethapyr, metolachlor, pendimethalin, permethrin, trifluralin). However, estimates of association for specific cancers were often imprecise because of small numbers of exposed cases, and clear monotonic exposure-response patterns were not always apparent. Exposure misclassification is also a concern in the AHS and may limit the analysis of exposure-response patterns. Epidemiologic evidence outside the AHS remains limited with respect to most of the observed associations, but animal toxicity data support the biological plausibility of relationships observed for alachlor, carbaryl, metolachlor, pendimethalin, permethrin, and trifluralin.
conclusionsContinued follow-up is needed to clarify associations reported to date. In particular, further evaluation of registered pesticides is warranted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.