Evidence map›Paper›PMID 20444566›Full record

ArticleMagnetic resonance imaging2010

Functional MRI and multivariate autoregressive models.

Baxter P Rogers, Santosh B Katwal, Victoria L Morgan, Christopher L Asplund, John C Gore

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 68 citations in OpenAlex.

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  18. Joint Estimation of Multiple Graphical Models from High Dimensional Time Series.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Baxter P RogersInstitute of Imaging Science, Vanderbilt University, Nashville, TN 37232-2310, USA. baxter.rogers@vanderbilt.edu
Santosh B Katwal
Victoria L Morgan
Christopher L Asplund
John C Gore
Vanderbilt University · US

Funding

Integrated Imaging of Brain Function at 7 TeslaR01EB000461 · NIBIB · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2002 to 2012
$9.4M
Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0M
Temporal Clustering Analysis for Detection of Irregular Transient fMRI ActivationR01NS055822 · NINDS · VANDERBILT UNIVERSITY · PI MORGAN, VICTORIA L · 2007 to 2009
$806k
EFFECTIVE CONNECTIVITY IN BRAIN IMAGING OF VISIONR03EY014437 · NEI · VANDERBILT UNIVERSITY · PI BLAKE, ROBERT RANDOLPH · 2003 to 2005
$453k
NEI NIH HHS 5R03EY014437NEI NIH HHS R03 EY014437NIBIB NIH HHS 5R01EB000461NIBIB NIH HHS R01 EB000461NIBIB NIH HHS T32 EB001628NINDS NIH HHS 5R01NS055822NINDS NIH HHS R01 NS055822
6 · The paper itself

Abstract

Connectivity refers to the relationships that exist between different regions of the brain. In the context of functional magnetic resonance imaging (fMRI), it implies a quantifiable relationship between hemodynamic signals from different regions. One aspect of this relationship is the existence of small timing differences in the signals in different regions. Delays of 100 ms or less may be measured with fMRI, and these may reflect important aspects of the manner in which brain circuits respond as well as the overall functional organization of the brain. The multivariate autoregressive time series model has features to recommend it for measuring these delays and is straightforward to apply to hemodynamic data. In this review, we describe the current usage of the multivariate autoregressive model for fMRI, discuss the issues that arise when it is applied to hemodynamic time series and consider several extensions. Connectivity measures like Granger causality that are based on the autoregressive model do not always reflect true neuronal connectivity; however, we conclude that careful experimental design could make this methodology quite useful in extending the information obtainable using fMRI.

Indexed as

AlgorithmsBrainBrain MappingHemodynamicsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingModels, NeurologicalMultivariate AnalysisRegression AnalysisTime Factors

Identifiers

PMID20444566
PMCPMC2940955
OpenAlexW2034112003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.