ArticleBMC pediatrics2010
Non invasive ventilation after extubation in paediatric patients: a preliminary study.
Article in BMC pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC).Intensive care medicine · 2017Guideline
- Trial
- Review
- Postextubation Noninvasive Respiratory Support in Children.Respiratory care · 2025Review
- Risk factors and outcomes of postoperative extubation failure in children with fourth ventricular tumors: a case control study.BMC pediatrics · 2024Article
- Pediatric Ventilator Liberation: One-Hour Versus Two-Hour Spontaneous Breathing Trials in a Single Center.Respiratory care · 2023Article
- Article
- Use of Dexamethasone to Prevent Extubation Failure in Pediatric Intensive Care Unit: A Randomized Controlled Clinical Trial.Journal of pediatric intensive care · 2022Article
- Ventilation Weaning and Extubation Readiness in Children in Pediatric Intensive Care Unit: A Review.Frontiers in pediatrics · 2022Review
- Risk factors and outcomes of extubation failure in a South African tertiary paediatric intensive care unit.The Southern African journal of critical care : the official journal of the Critical Care Society · 2022Article
- Feasibility of Pediatric Non-Invasive Respiratory Support in Low- and Middle-Income Countries.Indian pediatrics · 2021Review
- A comparative two-cohort study of pediatric patients with long term stay in ICUs.Scientific reports · 2021Article
- Use of Noninvasive Ventilation in Respiratory Failure After Extubation During Postoperative Care in Pediatrics.Pediatric cardiology · 2020Article
- Consideration of the respiratory support strategy of severe acute respiratory failure caused by SARS-CoV-2 infection in children.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Noninvasive Ventilation and High-Flow NasalSultan Qaboos University medical journal · 2018Review
- Comparison of Effort of Breathing for Infants on Nasal Modes of Respiratory Support.The Journal of pediatrics · 2017Article
- [Noninvasive ventilation in pediatric acute respiratory failure].Notfall & rettungsmedizin · 2017Review
- Efficacy and predictors of success of noninvasive ventilation for prevention of extubation failure in critically ill children with heart disease.Pediatric cardiology · 2013Article
- The number of failing organs predicts non-invasive ventilation failure in children with ALI/ARDS.Intensive care medicine · 2011Article
- Noninvasive positive pressure ventilation for acute respiratory failure in children: a concise review.Annals of intensive care · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-invasive ventilation (NIV) may be useful after extubation in children. Our objective was to determine postextubation NIV characteristics and to identify risk factors of postextubation NIV failure.
methodsA prospective observational study was conducted in an 8-bed pediatric intensive care unit (PICU). Following PICU protocol, NIV was applied to patients who had been mechanically ventilated for over 12 hours considered at high-risk of extubation failure -elective NIV (eNIV), immediately after extubation- or those who developed respiratory failure within 48 hours after extubation -rescue NIV (rNIV)-. Patients were categorized in subgroups according to their main underlying conditions. NIV was deemed successful when reintubation was avoided. Logistic regression analysis was performed in order to identify predictors of NIV failure.
resultsThere were 41 episodes (rNIV in 20 episodes). Success rate was 50% in rNIV and 81% in eNIV (p = 0.037). We found significant differences in univariate analysis between success and failure groups in respiratory rate (RR) decrease at 6 hours, FiO2 at 1 hour and PO2/FiO2 ratio at 6 hours. Neurologic condition was found to be associated with NIV failure. Multiple logistic regression analysis identified no variable as independent NIV outcome predictor.
conclusionsOur data suggest that postextubation NIV seems to be useful in avoiding reintubation in high-risk children when applied immediately after extubation. NIV was more likely to fail when ARF has already developed (rNIV), when RR at 6 hours did not decrease and if oxygen requirements increased. Neurologic patients seem to be at higher risk of reintubation despite NIV use.
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