Evidence map›Paper›PMID 20443818›Full record

ArticleClinical and translational science2008

MicroRNAs as new players in the genomic galaxy and disease puzzles.

Elisa Barbarotto, Paola Secchiero, Abhijit Dasgupta, Paolo Fortina, George A Calin, Terry Hyslop

Abstract read
In one paragraph

Article in Clinical and translational science, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisa BarbarottoDepartment of Morphology and Embryology, University of Ferrara, Ferrera, Italy.
Paola Secchiero
Abhijit Dasgupta
Paolo Fortina
George A Calin
Terry Hyslop

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abstract MicroRNAs (miRNAs) are a large family of short, single-stranded, highly conserved noncoding RNAs involved in gene regulation that can regulate gene expression through sequence-specific base pairing with target messenger RNAs (mRNAs). miRNAs have been implicated in the development of a wide variety of cancers as well as heart disease and other diseases. This review describes the role of miRNAs in human disease, methodology for evaluating miRNA gene expression, and the potential role of miRNAs as therapeutic agents and targets for the treatment of disease.

Indexed as

Gene Expression RegulationAnimalsCaenorhabditis elegansGene Expression ProfilingGene Expression Regulation, NeoplasticGenomicsHeart DiseasesHumansMicroRNAsModels, BiologicalNeoplasmsTissue DistributionMicroRNAs

Identifiers

PMID20443818
PMCPMC5439583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.