ArticleJournal of cell science2010
Sulf1A and HGF regulate satellite-cell growth.
Article in Journal of cell science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Estrogen-Related Receptor Alpha Promotes Skeletal Muscle Regeneration and Mitigates Muscular Dystrophy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy.Science advances · 2025Article
- Enhanced external counterpulsation improves dysfunction of forearm muscle caused by radial artery occlusion.Frontiers in cardiovascular medicine · 2023Article
- Growth Factors Do Not Improve Muscle Function in Young or AdultBiomedicines · 2022Article
- rHGF interacts with rIGF-1 to activate the satellite cells in the striated urethral sphincter in rats: a promising treatment for urinary incontinence?Archives of gynecology and obstetrics · 2018Article
- Identification of satellite cells from anole lizard skeletal muscle and demonstration of expanded musculoskeletal potential.Developmental biology · 2018Article
- Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.Histochemistry and cell biology · 2016Article
- SULF1/SULF2 reactivation during liver damage and tumour growth.Histochemistry and cell biology · 2016Article
- Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.Histochemistry and cell biology · 2016Article
- Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells.Skeletal muscle · 2014Article
- Muscle atrophy reversed by growth factor activation of satellite cells in a mouse muscle atrophy model.PloS one · 2014Article
- Follistatin-like 3 (FSTL3) mediated silencing of transforming growth factor β (TGFβ) signaling is essential for testicular aging and regulating testis size.Endocrinology · 2013Article
- Role of Sulf1A in Wnt1- and Wnt6-induced growth regulation and myoblast hyper-elongation.FEBS open bio · 2013Article
- Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Mammalian Sulf1 RNA alternative splicing and its significance to tumour growth regulation.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2012Article
- Syndecans in skeletal muscle development, regeneration and homeostasis.Muscles, ligaments and tendons journal · 2012Article
- Article
- Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration.Journal of cellular and molecular medicine · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The role of Sulf1A, sulfation and hepatocyte growth factor (HGF) in satellite-cell growth was examined in an in vitro model of dissociated whole skeletal muscle fibres. Pax7-positive quiescent satellite cells express little or no Sulf1A but show rapid re-expression in regenerating myoblasts and myotubes, similar to embryonic muscle and in vitro satellite cells preceding asynchronous MyoD activation. Once activated, Sulf1A and MyoD re-expression persists up to 72 hours in most satellite cells under normal culture conditions and following moderate changes in sulfation, whereas Sulf1A neutralisation by antibodies not only enhances satellite-cell proliferation but also downregulates MyoD and Pax7 expression in a large proportion of the satellite cells. The HGF exposure also induces similar but even more pronounced changes characterised by variable sulfation levels and rapid downregulation of MyoD and Pax7 without myogenin activation in a sub-set of cells. This Pax7-MyoD-myogenin-negative sub-population expresses Sulf1A and Myf5. The transfer of all such satellite-cell progenies onto gelatin-coated-substratum re-activates MyoD and Pax7 gene expression in all cells, thus detecting a distinct sub-population of satellite cells. We conclude that HGF and fine-tuned sulfation levels are major contributory factors controlling satellite-cell growth by regulating the relative activities of actively proliferating and differentiating cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.