Evidence map›Paper›PMID 20441783›Full record

ReviewAdvanced drug delivery reviews2010

Recombinant elastin-mimetic biomaterials: Emerging applications in medicine.

Wookhyun Kim, Elliot L Chaikof

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Engineering spatiotemporal organization and dynamics in synthetic cells.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021
    Review
  11. Article
  12. Article
  13. Protein-Engineered Functional Materials.Advanced healthcare materials · 2019
    Review
  14. Protein-Based Fiber Materials in Medicine: A Review.Nanomaterials (Basel, Switzerland) · 2018
    Review
  15. Rational design of fiber forming supramolecular structures.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
  16. Article
  17. Article
  18. Fabricated Elastin.Advanced healthcare materials · 2015
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wookhyun KimDepartment of Biomedical Engineering, Emory University/Georgia Institute of Technology, Atlanta, 30332, USA.
Elliot L Chaikof

Funding

MEMBRANE-MIMETIC ASSEMBLIES FOR ENDOTHELIAL MIGRATIONR01HL056819 · NHLBI · EMORY UNIVERSITY · PI CHAIKOF, ELLIOT · 1998 to 2016
$5.2M
A Bioinspired Small Diameter Vascular ConduitR01HL083867 · NHLBI · EMORY UNIVERSITY · PI CHAIKOF, ELLIOT · 2006 to 2010
$3.8M
Autogeneration of an Artery: A Biomimetric StrategyR01HL060464 · NHLBI · EMORY UNIVERSITY · PI CHAIKOF, ELLIOT · 1998 to 2007
$2.3M
NHLBI NIH HHS R01 HL056819NHLBI NIH HHS R01 HL060464NHLBI NIH HHS R01 HL083867
6 · The paper itself

Abstract

Biomaterials derived from protein-based block copolymers are increasingly investigated for potential application in medicine. In particular, recombinant elastin block copolymers provide significant opportunities to modulate material microstructure and can be processed in various forms, including particles, films, gels, and fiber networks. As a consequence, biological and mechanical responses of elastin-based biomaterials are tunable through precise control of block size and amino acid sequence. In this review, the synthesis of a set of elastin-mimetic triblock copolymers and their diverse processing methods for generating material platforms currently applied in medicine will be discussed.

Indexed as

AnimalsBiocompatible MaterialsBiomimetic MaterialsElastinHumansProtein EngineeringRecombinant ProteinsBiocompatible MaterialsElastinRecombinant Proteins

Identifiers

PMID20441783
PMCPMC2937194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.