ArticleIntensive care medicine2010
Transfusion practice and guidelines in Australian and New Zealand intensive care units.
Article in Intensive care medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03138200 (The Role of Central Venous Oxygen Saturation), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Recommendations on RBC Transfusion in General Critically Ill Children Based on Hemoglobin and/or Physiologic Thresholds From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Guideline
- Intravenous iron or placebo for anaemia in intensive care: the IRONMAN multicentre randomized blinded trial : A randomized trial of IV iron in critical illness.Intensive care medicine · 2016Trial
- An audit of platelet transfusions at a tertiary care center: New opportunities for patient blood management with the 2025 AABB/ICTMG platelet guidelines.Transfusion · 2026Article
- Reduced risk of perioperative blood transfusions in coronary surgery: A nationwide study over 18 years.Journal of cardiothoracic surgery · 2025Article
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- Blood Transfusion Practices in Intensive Care: A Prospective Observational Binational Study.Critical care explorations · 2025Observational
- Plasma transfusion in the intensive care unit.Transfusion · 2025Observational
- Platelet transfusions in adult ICU patients with thrombocytopenia: A sub-study of the PLOT-ICU inception cohort study.Acta anaesthesiologica Scandinavica · 2024Article
- Platelet transfusions in adult thrombocytopenic ICU patients: Protocol for a sub-study of the PLOT-ICU cohort.Acta anaesthesiologica Scandinavica · 2024Article
- Platelet versus fresh frozen plasma transfusion for coagulopathy in cardiac surgery patients.PloS one · 2024Article
- Transfusion practices in intensive care units: An Australian and New Zealand point prevalence study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023Article
- Patterns and determinants of blood transfusion in intensive care in Sweden between 2010 and 2018: A nationwide, retrospective cohort study.Transfusion · 2022Article
- Blood Ordering and Transfusion Practices: An Insight Toward Better Utility of Blood Products.Cureus · 2022Article
- Elevated IL-12, TNF-Journal of immunology research · 2020Article
- Iron Metabolism: An Emerging Therapeutic Target in Critical Illness.Critical care (London, England) · 2019Review
- Article
- Determinants and time to blood transfusion among thermal burn patients admitted to Mulago Hospital.BMC research notes · 2017Article
- Is platelet transfusion associated with hospital-acquired infections in critically ill patients?Critical care (London, England) · 2017Article
- Iron supplementation to treat anaemia in adult critical care patients: a systematic review and meta-analysis.Critical care (London, England) · 2016Article
- Platelet transfusions in cancer patients with hypoproliferative thrombocytopenia in the intensive care unit.Annals of intensive care · 2015Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the relationship between clinical practice and national guidelines for the transfusion of red blood cells (RBCs), fresh frozen plasma (FFP), platelets, and cryoprecipitate in Australian and New Zealand intensive care units (ICUs).
settingForty-seven ICUs over a 5-week period from August to September 2008.
designProspective, observational, multicentre, cohort study. PATIENTS: A total of 874 patients receiving any type of blood transfusion.
methodsAll patients who were transfused at least one unit of any blood component were included. Patient-specific and blood-component specific data were gathered. Pre-transfusion haemoglobin, platelet count, international normalised ratio (INR), and fibrinogen levels were compared to national guidelines.
resultsOf all 874 patients, 757 received RBCs (86.6%), 231 (26.4%) received platelets, 340 (38.9%) received FFP, and 78 (8.9%) received cryoprecipitate. Bleeding was the reason for administration of RBCs in 46%, FFP in 55%, and platelets in 47% of transfusions. The mean (SD) pre-transfusion haemoglobin was 77.6 (9.5) g/l, while the geometric means (95% CI) for platelet count, INR, and fibrinogen were 67.0 (59.7-75.3) x 10(9)/l, 1.84 (1.76-1.93), and 1.4 (1.1-1.8) g/l, respectively. The proportions of transfusions not adherent to guidelines were 2% for RBC, but 53% for platelets, 29% for FFP, and 88% for cryoprecipitate (RBC vs. other transfusion p < 0.001 for all).
conclusionsTransfusion practice of RBCs in Australian and New Zealand ICUs is restrictive and is concordant with guidelines. However, the transfusion of other blood components is not.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.