Evidence map›Paper›PMID 20440564›Full record

SynthesisTheoretical medicine and bioethics2010

Existential loneliness and end-of-life care: a systematic review.

Eric J Ettema, Louise D Derksen, Evert van Leeuwen

Abstract readSystematic Review
In one paragraph

Synthesis in Theoretical medicine and bioethics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Connected by Nature: Nature-Based Intervention to Support Young Adults with Advanced Cancer.International journal of environmental research and public health · 2026
    Article
  7. Experiences of loneliness among older deaf adults who use sign language.Journal of deaf studies and deaf education · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. [Loneliness at the end of life].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Perspectives on existential loneliness. Narrations by older people in different care contexts.International journal of qualitative studies on health and well-being · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric J EttemaDepartment of Metamedica, Section Philosophy and Medical Ethics, Vrije Universiteit Medical Centre Amsterdam, Amsterdam, The Netherlands. EJ.Ettema@vumc.nl
Louise D Derksen
Evert van Leeuwen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with a life-threatening illness can be confronted with various types of loneliness, one of which is existential loneliness (EL). Since the experience of EL is extremely disruptive, the issue of EL is relevant for the practice of end-of-life care. Still, the literature on EL has generated little discussion and empirical substantiation and has never been systematically reviewed. In order to systematically review the literature, we (1) identified the existential loneliness literature; (2) established an organising framework for the review; (3) conducted a conceptual analysis of existential loneliness; and (4) discussed its relevance for end-of-life care. We found that the EL concept is profoundly unclear. Distinguishing between three dimensions of EL-as a condition, as an experience, and as a process of inner growth-leads to some conceptual clarification. Analysis of these dimensions on the basis of their respective key notions-everpresent, feeling, defence; death, awareness, difficult communication; and inner growth, giving meaning, authenticity-further clarifies the concept. Although none of the key notions are unambiguous, they may function as a starting point for the development of care strategies on EL at the end of life.

Indexed as

Attitude to DeathConcept FormationLonelinessTerminal CareAdaptation, PsychologicalAttitude of Health PersonnelCommunicationEmotionsHumansPalliative CareQuality of LifeSocial IsolationSpiritualityThinking

Identifiers

PMID20440564
PMCPMC2866502

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.