ReviewNature reviews. Cardiology2010
Early identification of atherosclerotic disease by noninvasive imaging.
Review in Nature reviews. Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Hypertriglyceridemic waist and subclinical atherosclerosis: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- The high-risk plaque initiative: primary prevention of atherothrombotic events in the asymptomatic population.Current atherosclerosis reports · 2011Trial
- Metabolic control of smooth muscle cell phenotype switching in atherosclerosis.Science advances · 2026Article
- Circulating extracellular microRNAs as tissue-specific biomarkers of human health and disease.Nature communications · 2026Article
- Pregnancy as an Early Cardiovascular Moment: Peripartum Cardiovascular Health.Circulation research · 2023Review
- Nonlinear correlation between fatty liver index and carotid intima media thickness among individuals undergoing health examination.Frontiers in endocrinology · 2023Article
- Management of oxidative stress and inflammation in cardiovascular diseases: mechanisms and challenges.Environmental science and pollution research international · 2021Review
- Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches.Theranostics · 2018Review
- Systems Biology and Noninvasive Imaging of Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2016Review
- Contrast Ultrasound Imaging Does Not Affect Heat Shock Protein 70 Expression in Cholesterol-Fed Rabbit Aorta.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2015Article
- SPECT/CT Imaging of High-Risk Atherosclerotic Plaques using Integrin-Binding RGD Dimer Peptides.Scientific reports · 2015Article
- Imaging subclinical atherosclerosis: is it ready for prime time? A review.Journal of cardiovascular translational research · 2014Review
- Multimodality PET/MRI agents targeted to activated macrophages.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014Article
- Investigation on cardiovascular risk prediction using physiological parameters.Computational and mathematical methods in medicine · 2013Review
- Heartache and heartbreak--the link between depression and cardiovascular disease.Nature reviews. Cardiology · 2012Review
- Receptor-targeted iron oxide nanoparticles for molecular MR imaging of inflamed atherosclerotic plaques.Biomaterials · 2011Article
- Nanotechnology for synthetic high-density lipoproteins.Trends in molecular medicine · 2010Article
- The role of noninvasive imaging in promoting cardiovascular health.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2010Review
- Early identification of cardiovascular risk using genomics and proteomics.Nature reviews. Cardiology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease (CVD) is the leading cause of death worldwide, and its prevalence is expected to increase further, which will be associated with a substantial economic burden. High-risk or vulnerable plaques and, indirectly, the burden of atherosclerotic disease, are responsible for most major cardiovascular events. Most of the current prevention strategies are focused on identifying and managing the established risk factors (smoking, hypertension, hypercholesterolemia, diabetes, obesity, physical inactivity) for atherosclerosis. Another opportunity for further characterizing the population at high CVD risk would be to measure the occurrence and progression of subclinical (asymptomatic) atherosclerotic burden. The detection of subclinical atherosclerosis and high-risk plaques, if proven to predict cardiovascular events, may enable the establishment of earlier control of CVD risk factors and help preventing CVD. In this Review, we address the potential progress in CVD prevention brought about by the use of noninvasive imaging techniques to identify subclinical atherosclerosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.