ArticleThe American journal of tropical medicine and hygiene2010
A comparative analysis of coprologic diagnostic methods for detection of Toxoplama gondii in cats.
Article in The American journal of tropical medicine and hygiene, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Feline enteropathogens and molecular diagnostics: benefits, limitations and clinical applications.Journal of feline medicine and surgery · 2025Review
- Evaluating the significance of Toxoplasma gondii sporozoite antibodies in cats: a pilot study.Parasites & vectors · 2024Article
- Rapid and visual detection of Toxoplasma gondii oocyst in cat feces using loop-mediated isothermal amplification (LAMP) assay.Scientific reports · 2023Article
- A real-time quantitative polymerase chain reaction for the specific detection of Hammondia hammondi and its differentiation from Toxoplasma gondii.Parasites & vectors · 2021Article
- Seroprevalence ofFood and waterborne parasitology · 2020Article
- Molecular Detection and Genetic Diversity ofPathogens (Basel, Switzerland) · 2020Article
- Sensitive, quantitative detection ofInternational journal for parasitology. Parasites and wildlife · 2020Article
- Detection ofVeterinary world · 2018Article
- Surrogate hosts: Hunting dogs and recolonizing grey wolves share their endoparasites.International journal for parasitology. Parasites and wildlife · 2017Article
- Development of a loop-mediated isothermal amplification technique and comparison with quantitative real-time PCR for the rapid visual detection of canine neosporosis.Parasites & vectors · 2017Article
- Detection of Toxoplasma gondii in faeces of privately owned cats using two PCR assays targeting the B1 gene and the 529-bp repetitive element.Parasitology research · 2017Article
- Detection of Toxoplasma gondii DNA by qPCR in the feces of a cat that recently ingested infected prey does not necessarily imply oocyst shedding.Parasite (Paris, France) · 2016Article
- Seroepidemiology of Toxoplasmosis among People Having Close Contact with Animals.Frontiers in immunology · 2015Article
- High prevalence of Toxoplasma gondii oocyst shedding in stray and pet cats (Felis catus) in Virginia, United States.Parasites & vectors · 2013Article
- Prevalence of Toxoplasma gondii antibodies, circulating antigens and DNA in stray cats in Shanghai, China.Parasites & vectors · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relative role of transmission of Toxoplasma gondii infection from cats to humans appears to have recently increased in certain areas. Large-scale screening of oocyst shedding in cats cannot rely on microscopy because oocyst identification lacks sensitivity and specificity, or on bioassays, which require test animals and weeks before examination. We compared a sensitive and species-specific coprologic-polymerase chain reaction (copro-PCR) for detection of T. gondii infected cats with microscopy and a bioassay. In experimentally infected cats followed over time, microscopy was positive occasionally, and positive copro-PCR and bioassay results were obtained continuously from days 2 to 24 post-infection. The copro-PCR is at least as sensitive and specific as the bioassay and is capable of detecting infective oocysts during cat infection. Therefore, this procedure can be used as the new gold standard for determining potential cat infectivity. Its technologic advantages over the bioassay make it superior for large-scale screening of cats.
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