Evidence map›Paper›PMID 20438325›Full record

Trial reportJournal of medicinal food2010

Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study.

Wilfred R Pigeon, Michelle Carr, Colin Gorman, Michael L Perlis

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of medicinal food, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 4 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05953324 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effects Of Kiwifruit Consumption On Sleep Quality, Fatigue And BMI In Saudi Students With Poor Sleep Quality: A 6-Week Pilot Randomized Controlled Trial

TypeinterventionalSponsorUmm Al-Qura UniversityRan2022 to 2022Enrolled26ConditionsSleep Disturbance, Fatigue, Body WeightArmsKiwifruit
NCT06299488 nacompletednot on this mapstarted 2023, after this paper: background citation

Combined Effects of Prunus Cerasus (Montmorency Tart Cherry) and Apocynum Venetum (Venetron®) On Sleep and Anxiety in Adults With Insomnia

TypeinterventionalSponsorLakshmi Nutraceuticals LLCRan2023 to 2023Enrolled77ConditionsInsomniaArmsSip2Sleep: Montmorency Cherry and Apocynum Venetum
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 4 syntheses or guidelines pooled it, 155 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wilfred R PigeonSleep & Neurophysiology Research Laboratory, Department of Psychiatry, University of Rochester Medical Center, Rochester, New York 14642, USA. wilfred_pigeon@urmc.rochester.edu
Michelle Carr
Colin Gorman
Michael L Perlis
University of Rochester Medical Center · USCalifornia University of Pennsylvania · US

Funding

The Psychoneuroimmunology of Insomnia: Response to a Vaccine ChallengeK23NR010408 · NINR · UNIVERSITY OF ROCHESTER · PI PIGEON, WILFRED R · 2007 to 2009
$420k
NIMH NIH HHS L30 MH087269NINR NIH HHS K23 NR010408
6 · The paper itself

Abstract

This study ascertained whether a proprietary tart cherry juice blend (CherryPharm, Inc., Geneva, NY, USA) associated with anecdotal reports of sleep enhancement improves subjective reports of insomnia compared to a placebo beverage. The pilot study used a randomized, double-blind, crossover design where each participant received both treatment and placebo for 2 weeks with an intervening 2-week washout period. Sleep continuity (sleep onset, wake after sleep onset, total sleep time, and sleep efficiency) was assessed by 2-week mean values from daily sleep diaries and disease severity by the Insomnia Severity Index in a cohort of 15 older adults with chronic insomnia who were otherwise healthy. The tart cherry juice beverage was associated with statistically significant pre- to post-treatment improvements on all sleep variables. When compared to placebo, the study beverage produced significant reductions in insomnia severity (minutes awake after sleep onset); no such improvements were observed for sleep latency, total sleep time, or sleep efficiency compared to placebo. Effect sizes were moderate and in some cases negligible. The results of this pilot study suggest that CherryPharm, a tart cherry juice blend, has modest beneficial effects on sleep in older adults with insomnia with effect sizes equal to or exceeding those observed in studies of valerian and in some, but not all, studies of melatonin, the two most studied natural products for insomnia. These effects, however, were considerably less than those for evidence-based treatments of insomnia: hypnotic agents and cognitive-behavioral therapies for insomnia.

Indexed as

BeveragesAgedAged, 80 and overCross-Over StudiesFemaleHumansMalePilot ProjectsPrunusSleepSleep Initiation and Maintenance Disorders

Identifiers

PMID20438325
PMCPMC3133468
OpenAlexW1983372085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.