ArticleThe Plant cell2010
TCP1 modulates brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana.
Article in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
106 citing papers in PubMed, 204 citations in OpenAlex.
- Jujube Witches' Broom Phytoplasma Effectors SJP1/2 Manipulate the ZjTCP2-ZjTCP1 Cascade to Repress Leaf Cell Proliferation in Jujube.Molecular plant pathology · 2026Article
- Morphological responses of Arabidopsis thaliana wild type and photoreceptor genotypes to narrowband UV radiation generated by LEDs.Plant biology (Stuttgart, Germany) · 2025Article
- Genome-wide identification of TCP gene family and gene editing of BjTCP18 genes increases branching in Brassica juncea.Functional & integrative genomics · 2025Article
- Manipulating brassinosteroid signaling pathway to genetically improve horticultural plants.aBIOTECH · 2025Review
- Genome-wide identification and expression analysis of TCP transcription factors in Chrysanthemum indicum reveals their critical role in the response to various abiotic stresses.BMC plant biology · 2025Article
- Wo interacts with SlTCP25 to regulate type I trichome branching in tomato.Horticulture research · 2025Article
- Comparative transcriptome analysis reveals potential regulatory genes involved in the development and strength formation of maize stalks.BMC plant biology · 2025Article
- Unveiling kiwifruit TCP genes: evolution, functions, and expression insights.Plant signaling & behavior · 2024Article
- Interaction between plant-specific transcription factors TCP and YABBY expressed in the tendrils of the melon Cucumis melo.Scientific reports · 2024Article
- Molecular Lesions in BRI1 and Its Orthologs in the Plant Kingdom.International journal of molecular sciences · 2024Review
- Homoeologous exchanges contribute to branch angle variations in rapeseed: Insights from transcriptome, QTL-seq and gene functional analysis.Plant biotechnology journal · 2024Article
- Article
- Deciphering the maize gene ZmGF14-3: implications for plant height based on co-expression networks.Frontiers in plant science · 2024Article
- Identification of Functional Brassinosteroid Receptor Genes in Oaks and Functional Analysis ofInternational journal of molecular sciences · 2023Article
- Jasmonates regulate apical hook development by repressing brassinosteroid biosynthesis and signaling.Plant physiology · 2023Article
- Genome-Wide Identification of TCP Gene Family inInternational journal of molecular sciences · 2023Article
- TCP Transcription Factors in Plant Reproductive Development: Juggling Multiple Roles.Biomolecules · 2023Review
- Early Fruit Development Regulation-Related Genes Concordantly Expressed with TCP Transcription Factors in Tomato (Current issues in molecular biology · 2023Article
- Genome-wide identification of theFrontiers in plant science · 2023Article
- Genome-wide identification and expression pattern analysis of the TCP transcription factor family inPlant signaling & behavior · 2022Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brassinosteroids (BRs) are essential phytohormones regulating normal plant growth and development. TCP1, a gene thought to be involved in floral organ symmetric control, was identified as a genetic suppressor of a weak BR receptor mutant, bri1-5, in an activation-tagging genetic screen. TCP1 encodes a putative transcription factor possessing a basic helix-loop-helix domain. The dominant allele of TCP1, tcp1-1D, suppresses the defective phenotypes of bri1-5. Overexpression of a dominant-negative form of TCP1, TCP1-SRDX, with a 12-amino acid repressor sequence fused to TCP1 at its C terminus, results in dwarfed plants resembling BR-deficient or insensitive mutants. The defective phenotypes can be rescued by exogenously applied brassinolide but cannot be recovered by auxins, gibberellins, or cytokinins. BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis. Real-time RT-PCR analysis further demonstrated that TCP1 regulates the transcription levels of DWF4, and chromatin immunoprecipitation experiments showed that TCP1 indeed interacts with the DWF4 promoter. Confocal microscopy indicated that TCP1 is mainly confined to the nucleus. The expression of TCP1 appears to be regulated by BR levels. These studies demonstrate another level of regulation through which BRs mediate plant growth and development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.