Evidence map›Paper›PMID 20435161›Full record

ArticleJournal of biomedical informatics2010

DSGeo: software tools for cross-platform analysis of gene expression data in GEO.

Ronilda Lacson, Erik Pitzer, Jihoon Kim, Pedro Galante, Christian Hinske, Lucila Ohno-Machado

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Translational bioinformatics: linking knowledge across biological and clinical realms.Journal of the American Medical Informatics Association : JAMIA
    Article
  6. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes.Journal of the American Medical Informatics Association : JAMIA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ronilda LacsonDecision Systems Group, Brigham and Women's Hospital, Boston, MA, USA. rclacson@mit.edu
Erik Pitzer
Jihoon Kim
Pedro Galante
Christian Hinske
Lucila Ohno-Machado

Funding

iDASH: Integrating Data for Analysis, Anonymization, and SharingU54HL108460 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2010 to 2015
$19.1M
Global Health Informatics for Cancer ResearchD43TW007015 · FIC · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2004 to 2013
$2.2M
Assessing quality of individual predictions in medical decision support systemsR01LM009520 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2007 to 2010
$1.4M
FIC NIH HHS D43 TW007015FIC NIH HHS D43TW007015NHLBI NIH HHS U54 HL108460NLM NIH HHS R01 LM009520NLM NIH HHS R01LM009520
6 · The paper itself

Abstract

The Gene Expression Omnibus (GEO) is the largest resource of public gene expression data. While GEO enables data browsing, query and retrieval, additional tools can help realize its potential for aggregating and comparing data across multiple studies and platforms. This paper describes DSGeo-a collection of valuable tools that were developed for annotating, aggregating, integrating, and analyzing data deposited in GEO. The core set of tools include a Relational Database, a Data Loader, a Data Browser, and an Expression Combiner and Analyzer. The application enables querying for specific sample characteristics and identifying studies containing samples that match the query. The Expression Combiner application enables normalization and aggregation of data from these samples and returns these data to the user after filtering, according to the user's preferences. The Expression Analyzer allows simple statistical comparisons between groups of data. This seamless integration makes annotated cross-platform data directly available for analysis.

Indexed as

Gene Expression ProfilingInformation Storage and RetrievalMedical Informatics ApplicationsSoftwareAnimalsComputational BiologyComputer Communication NetworksHumansUser-Computer Interface

Identifiers

PMID20435161
PMCPMC2934864

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.