ReviewMethods (San Diego, Calif.)2010
DNA methylation profiling using HpaII tiny fragment enrichment by ligation-mediated PCR (HELP).
Review in Methods (San Diego, Calif.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Navigating the pitfalls of mapping DNA and RNA modifications.Nature reviews. Genetics · 2023Review
- Multi-omics integration strategies for animal epigenetic studies - A review.Animal bioscience · 2021Article
- Intrauterine Programming of Diabetes Induced Cardiac Embryopathy.Diabetes & obesity international journal · 2019Article
- The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma.JCI insight · 2018Article
- Sexual dimorphism in epigenomic responses of stem cells to extreme fetal growth.Nature communications · 2014Article
- DNA methylation is developmentally regulated for genes essential for cardiogenesis.Journal of the American Heart Association · 2014Article
- Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.Genome research · 2013Article
- Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease?Seminars in nephrology · 2013Review
- Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma.Scientific reports · 2013Article
- Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development.Genome biology · 2013Article
- MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples.Epigenomics · 2012Article
- Anticancer activity of green tea polyphenols in prostate gland.Oxidative medicine and cellular longevity · 2012Review
- Using DNA methylation to understand biological consequences of genetic variability.Neuro-degenerative diseases · 2012Review
- Advances in epigenetics and epigenomics for neurodegenerative diseases.Current neurology and neuroscience reports · 2011Review
- Epigenome-wide association studies for common human diseases.Nature reviews. Genetics · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The HELP assay is a technique that allows genome-wide analysis of cytosine methylation. Here we describe the assay, its relative strengths and weaknesses, and the transition of the assay from a microarray to massively-parallel sequencing-based foundation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.