Evidence map›Paper›PMID 20434061›Full record

ArticleEating behaviors2010

Circulating leptin moderates the effect of stress on snack intake independent of body mass.

Bradley M Appelhans

Open access · greenAbstract read
In one paragraph

Article in Eating behaviors, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Glucocorticoids, stress and eating: The mediating role of appetite-regulating hormones.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  3. Article
  4. Article
  5. Leptin regulates dopamine responses to sustained stress in humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Bradley M AppelhansDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, USA. brad_appelhans@rush.edu
Northwestern University · US

Funding

WOMEN'S INTERAGENCY HIV STUDY (WIHS) INTENSIVE PHARMACOKINETICS STUDYM01RR000048 · NCRR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RAMSEY-GOLDMAN, ROSALIND · 1985 to 2007
$21.1M
Postdoctoral Training Program in Cancer EpidemiologyR25CA100600 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI VAN HORN, LINDA VERNER · 2004 to 2008
$2.0M
NCI NIH HHS R25 CA100600NCI NIH HHS R25-CA100600NCRR NIH HHS M01-RR-00048
6 · The paper itself

Abstract

Prior studies have demonstrated influences of leptin on hunger and satiety, the processing of food reward, and taste and palatability perception. This pilot study tested whether leptin accounts for variability in stress-induced changes in snack intake, and explored potential mechanisms underlying this effect. Thirty-four normal weight and class I obese women were exposed to a 30-minute mental stressor and a non-stressful control task in counterbalanced order on consecutive days. Higher serum leptin concentrations predicted decreases in snack intake following the stressor relative to the control condition. Leptin was not a significant predictor of overall hunger or stress-induced changes in hunger, but was associated with greater perceived palatability of one of the four snacks. Overall, findings suggest that leptin may moderate the effect of stress on energy intake through non-homeostatic mechanisms.

Indexed as

Body Mass IndexAdultBody WeightEatingFemaleHumansLeptinMiddle AgedNeuropsychological TestsObesityPilot ProjectsStress, PsychologicalLeptin

Identifiers

PMID20434061
PMCPMC2864773
OpenAlexW2004565770

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.