ArticleBMC infectious diseases2010
Lives saved by Global Fund-supported HIV/AIDS, tuberculosis and malaria programs: estimation approach and results between 2003 and end-2007.
Article in BMC infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Unraveling the HIV-malaria interactions: a bibliometric analysis of global research trends and emerging insights.Frontiers in microbiology · 2025Pooled it
- Plasmonic coffee-ring biosensing for AI-assisted point-of-care diagnostics.Nature communications · 2025Article
- A Comprehensive Approach to Assuring Quality of Laboratory Testing in HIV Surveys: Lessons Learned From the Population-Based HIV Impact Assessment Project.Journal of acquired immune deficiency syndromes (1999) · 2021Article
- HIV Policy Advancements in PEPFAR Partner countries: a review of data from 2010-2016.Global public health · 2021Review
- Five insights from the Global Burden of Disease Study 2019.Lancet (London, England) · 2020Review
- Diagnostics as the Key to Advances in Global Health: Proposed Methods for Making Reliable Diagnostics Widely Available.Journal of medical devices · 2020Article
- Global palliative radiotherapy: a framework to improve access in resource-constrained settings.Annals of palliative medicine · 2019Review
- Spectrum-Malaria: a user-friendly projection tool for health impact assessment and strategic planning by malaria control programmes in sub-Saharan Africa.Malaria journal · 2017Article
- Adding interventions to mass measles vaccinations in India.Bulletin of the World Health Organization · 2016Article
- Global health initiatives in Africa - governance, priorities, harmonisation and alignment.BMC health services research · 2016Review
- Modeling Key Malaria Drugs' Impact on Global Health: A Reason to Invest in the Global Health Impact Index.The American journal of tropical medicine and hygiene · 2016Article
- The Global Health Impact Index: Promoting Global Health.PloS one · 2015Article
- Sixty years trying to define the malaria burden in Africa: have we made any progress?BMC medicine · 2014Article
- Vector control programs in Saint Johns County, Florida and Guayas, Ecuador: successes and barriers to integrated vector management.BMC public health · 2014Article
- Is health aid reaching the poor? Analysis of household data from aid recipient countries.PloS one · 2014Article
- Potential impact of the US President's Emergency Plan for AIDS relief on the tuberculosis/HIV coepidemic in selected Sub-Saharan African countries.The Journal of infectious diseases · 2013Article
- Analysis of human resources for health strategies and policies in 5 countries in Sub-Saharan Africa, in response to GFATM and PEPFAR-funded HIV-activities.Globalization and health · 2013Article
- Saving lives in health: global estimates and country measurement.PLoS medicine · 2013Article
- Methodological and policy limitations of quantifying the saving of lives: a case study of the Global Fund's approach.PLoS medicine · 2013Article
- Is passive diagnosis enough? The impact of subclinical disease on diagnostic strategies for tuberculosis.American journal of respiratory and critical care medicine · 2013Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince 2003, the Global Fund has supported the scale-up of HIV/AIDS, tuberculosis and malaria control in low- and middle-income countries. This paper presents and discusses a methodology for estimating the lives saved through selected service deliveries reported to the Global Fund.
methodsGlobal Fund-supported programs reported, by end-2007, 1.4 million HIV-infected persons on antiretroviral treatment (ARV), 3.3 million new smear-positive tuberculosis cases detected in DOTS (directly observed TB treatment, short course) programs, and 46 million insecticide-treated mosquito nets (ITNs) delivered. We estimated the corresponding lives saved using adaptations of existing epidemiological estimation models.
resultsBy end-2007, an estimated 681,000 lives (95% uncertainty range 619,000-774,000) were saved and 1,097,000 (993,000-1,249,000) life-years gained by ARV. DOTS treatment would have saved 1.63 million lives (1.09-2.17 million) when compared against no treatment, or 408,000 lives (265,000-551,000) when compared against non-DOTS treatment. ITN distributions in countries with stable endemic falciparum malaria were estimated to have achieved protection from malaria for 26 million of child-years at risk cumulatively, resulting in 130,000 (27,000-232,000) under-5 deaths prevented.
conclusionsThese results illustrate the scale of mortality effects that supported programs may have achieved in recent years, despite margins of uncertainty and covering only selected intervention components. Evidence-based evaluation of disease impact of the programs supported by the Global Fund with international and in-country partners must be strengthened using population-level data on intervention coverage and demographic outcomes, information on quality of services, and trends in disease burdens recorded in national health information systems.
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