ArticleEvolution & development
Silencing of an abdominal Hox gene during early development is correlated with limb development in a crustacean trunk.
Article in Evolution & development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Article
- Expression of posterior Hox genes and opisthosomal appendage development in a mygalomorph spider.Development genes and evolution · 2023Article
- Unexpected UBX expression in the maxilliped of the mystacocarid crustacean Derocheilocharis remanei-evidence for a different way of making a maxilliped?Development genes and evolution · 2017Article
- Mechanisms of Specificity for Hox Factor Activity.Journal of developmental biology · 2016Article
- Hox genes, evo-devo, and the case of the ftz gene.Chromosoma · 2016Review
- A stranger in a strange land: the utility and interpretation of heterologous expression.Frontiers in plant science · 2015Article
- Divergent role of the Hox gene Antennapedia in spiders is responsible for the convergent evolution of abdominal limb repression.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Cloning and characterization of β-catenin gene in early embryonic developmental stage of Artemia sinica.Molecular biology reports · 2012Article
- Surprising flexibility in a conserved Hox transcription factor over 550 million years of evolution.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We tested whether Artemia abd-A could repress limbs in Drosophila embryos, and found that although abd-A transcripts were produced, ABD-A protein was not. Similarly, developing Artemia epidermal cells showed expression of abd-A transcripts without accumulation of ABD-A protein. This finding in Artemia reveals a new variation in Hox gene function that is associated with morphological evolution. In this case, a HOX protein expression pattern is completely absent during early development, although the HOX protein is expressed at later stages in the central nervous system in a "homeotic-like" pattern. The combination of an absence of ABD-A protein expression in the Artemia limb primordia and the weak repressive function of Artemia UBX protein on the limb-promoting gene Dll are likely to be two reasons why homonomous limbs develop throughout the entire Artemia trunk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.