Evidence map›Paper›PMID 20432449›Full record

ArticleJournal of cellular physiology2010

Histone chaperones, histone acetylation, and the fluidity of the chromogenome.

Jeffrey C Hansen, Jennifer K Nyborg, Karolin Luger, Laurie A Stargell

Abstract read
In one paragraph

Article in Journal of cellular physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Regulation of Adaptive Immune Cells by Sirtuins.Frontiers in endocrinology · 2019
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Nucleosome distribution and linker DNA: connecting nuclear function to dynamic chromatin structure.Biochemistry and cell biology = Biochimie et biologie cellulaire · 2011
    Review
  17. Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeffrey C HansenDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA. jeffrey.c.hansen@colostate.edu
Jennifer K Nyborg
Karolin Luger
Laurie A Stargell

Funding

TRANSCRIPTIONAL REGULATION BY THE HTLV-I TAX PROTEINR01CA055035 · NCI · COLORADO STATE UNIVERSITY-FORT COLLINS · PI NYBORG, JENNIFER K. · 1994 to 2013
$3.9M
Structure and Function of Nucleosome Assembly Protein 1R01GM067777 · NIGMS · UNIVERSITY OF COLORADO · PI LUGER, KAROLIN · 2003 to 2015
$3.7M
CHROMATIN STRUCTURE AND STABILITY IN THE SOLUTION STATER01GM045916 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI HANSEN, JEFFREY C · 1996 to 2012
$3.3M
Structure of nucleosomes in complex with transcriptional regulatorsR01GM061909 · NIGMS · COLORADO STATE UNIVERSITY-FORT COLLINS · PI LUGER, KAROLIN · 2000 to 2009
$2.0M
NCI NIH HHS 2 R01 CA055035NCI NIH HHS R01 CA055035NIGMS NIH HHS 1 R01 GM067777NIGMS NIH HHS 2 R01 GM045916NIGMS NIH HHS 2 R01 GM061909NIGMS NIH HHS R01 GM045916NIGMS NIH HHS R01 GM061909NIGMS NIH HHS R01 GM067777
6 · The paper itself

Abstract

The "chromogenome" is defined as the structural and functional status of the genome at any given moment within a eukaryotic cell. This article focuses on recently uncovered relationships between histone chaperones, post-translational acetylation of histones, and modulation of the chromogenome. We emphasize those chaperones that function in a replication-independent manner, and for which three-dimensional structural information has been obtained. The emerging links between histone acetylation and chaperone function in both yeast and higher metazoans are discussed, including the importance of nucleosome-free regions. We close by posing many questions pertaining to how the coupled action of histone chaperones and acetylation influences chromogenome structure and function.

Indexed as

AcetylationAnimalsChromosomesGenomeHistone ChaperonesHistonesHumansNucleosomesHistone ChaperonesHistonesNucleosomes

Identifiers

PMID20432449
PMCPMC3184832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.