ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2010
Patients with coronary artery disease not amenable to traditional revascularization: prevalence and 3-year mortality.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of Curative Effect Evaluation of DanLou Tablet on Coronary Artery Disease Not Amenable to Revascularization on the Basis of Western Medicine Therapy
Study of Curative Effect Evaluation of Shexiang Baoxin Pill on Coronary Artery Disease Not Amenable to Revascularization on the Basis of Western Medicine Therapy
Coronary ARteriogenesis With Combined Heparin and EXercise Therapy in Chronic Refractory Angina
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cardiac shock-wave therapy in the treatment of coronary artery disease: systematic review and meta-analysis.Cardiovascular ultrasound · 2017Pooled it
- Impact of Cell Therapy on Myocardial Perfusion and Cardiovascular Outcomes in Patients With Angina Refractory to Medical Therapy: A Systematic Review and Meta-Analysis.Circulation research · 2016Pooled it
- The effect of external counterpulsation on intrinsic myocardial function evaluated by speckle tracking echocardiography in refractory angina patients: a randomized controlled trial.The international journal of cardiovascular imaging · 2021Trial
- The effect of cardiac shock wave therapy on myocardial function and perfusion in the randomized, triple-blind, sham-procedure controlled study.Cardiovascular ultrasound · 2019Trial
- A multicenter trial of extracorporeal cardiac shock wave therapy for refractory angina pectoris: report of the highly advanced medical treatment in Japan.Heart and vessels · 2019Trial
- Trial
- Effect of Permanent Right Internal Mammary Artery Closure on Coronary Collateral Function and Myocardial Ischemia.Circulation. Cardiovascular interventions · 2017Trial
- Efficacy of a device to narrow the coronary sinus in refractory angina.The New England journal of medicine · 2015Trial
- Safety and efficacy of extracorporeal shock wave myocardial revascularization therapy for refractory angina pectoris.Mayo Clinic proceedings · 2014Trial
- Trial
- Pacing to reduce refractory angina in patients with severe coronary artery disease: a crossover pilot trial.Journal of cardiovascular translational research · 2012Trial
- [Coronary artery disease multivessel not amenable to revascularization: contemporary cohort].Revista medica del Instituto Mexicano del Seguro Social · 2024Observational
- Coronary Sinus Reducer Therapy for Refractory Angina and its Role in Modern Interventional Practice: A Contemporary Review.Interventional cardiology (London, England) · 2024Review
- A budget impact model and a cost-utility analysis of reducer device (Neovasc) in patients with refractory angina.Frontiers in cardiovascular medicine · 2024Article
- Pre-arterialization of coronary veins prior to retroperfusion of ischemic myocardium: percutaneous closure device.Frontiers in cardiovascular medicine · 2023Article
- Therapeutic Angiogenesis Using Autologous CD34-Positive Cells for Vascular Diseases.Annals of vascular diseases · 2022Article
- Contemporary Management of Refractory Angina.Interventional cardiology clinics · 2022Review
- Optimization of cardiac resynchronization therapy based on a cardiac electromechanics-perfusion computational model.Computers in biology and medicine · 2022Article
- The Coronary Sinus Reducer; 5-year Dutch experience.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2021Article
- Son of a Lesser God: The Case of Cell Therapy for Refractory Angina.Frontiers in cardiovascular medicine · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the contemporary prevalence of and mortality in patients with coronary artery disease (CAD) not amenable to revascularization.
backgroundA growing number of patients have severe CAD with ongoing angina despite optimal medical therapy which is not amenable to traditional revascularization. Limited data exist on contemporary prevalence and outcome for these patients.
methodsClinical and angiographic data were reviewed for 493 consecutive patients undergoing coronary angiography and revascularization if indicated. Patients were categorized into six groups: (1) normal coronary arteries, (2) CAD <70%, (3) CAD >70% with complete revascularization by percutaneous intervention or coronary artery bypass grafting, (4) CAD >70% with partial revascularization, (5) CAD >70% treated medically, and (6) CAD >70% on optimal medical therapy with no revascularization option. All-cause mortality at 3 years was determined.
resultsPrevalence for groups 1-6 was 14.8, 19.5, 36.9, 12.8, 9.3, and 6.7%, respectively. Three-year mortality increased with angiographic severity of CAD: 2.7, 6.3, 8.2, 12.7, 17.4, and 15.2%, respectively. Patients with incomplete revascularization (groups 4-6, n = 142) had higher mortality than completely revascularized patients (groups 1-3, n = 351): 14.8 vs. 6.6% (P = 0.004).
conclusionsIn a contemporary series of patients undergoing coronary angiography, 28.8% (142/493) of patients had significant CAD and did not undergo complete revascularization, including 12.8% partially revascularized, 9.3% managed medically, and 6.7% with "no-option." These patients had higher mortality at 3 years (14.8 vs. 6.6%, P = 0.004) when compared with completely revascularized patients.
Indexed as
Identifiers
20432394What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.