ArticleMagnetic resonance in medicine2010
Magnetic nanoparticles for imaging dendritic cells.
Article in Magnetic resonance in medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- In vivo tracking of adenoviral-transduced iron oxide-labeled bone marrow-derived dendritic cells using magnetic particle imaging.European radiology experimental · 2023Article
- Progress in nanoparticle-based regulation of immune cells.Medical review (2021) · 2023Review
- Nanotech Probes: A Revolution in Cancer Diagnosis.Frontiers in oncology · 2022Review
- Improving Tumor Retention of Effector Cells in Adoptive Cell Transfer Therapies by Magnetic Targeting.Pharmaceutics · 2020Review
- Lipopolysaccharide Induced Opening of the Blood Brain Barrier on Aging 5XFAD Mouse Model.Journal of Alzheimer's disease : JAD · 2019Article
- Lipopeptide-Coated Iron Oxide Nanoparticles as Potential Glycoconjugate-Based Synthetic Anticancer Vaccines.ACS applied materials & interfaces · 2015Article
- The effect of superparamagnetic iron oxide with iRGD peptide on the labeling of pancreatic cancer cells in vitro: a preliminary study.BioMed research international · 2014Article
- A comprehensive analysis of transfection-assisted delivery of iron oxide nanoparticles to dendritic cells.Nanomedicine : nanotechnology, biology, and medicine · 2013Article
- Article
- In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).Molecular imaging and biology · 2012Article
- Mechanisms of dendritic cell trafficking across the blood-brain barrier.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2012Review
- Multimodal imaging of dendritic cells using a novel hybrid magneto-optical nanoprobe.Nanomedicine : nanotechnology, biology, and medicine · 2011Article
- Fluorescent magnetic hybrid nanoprobe for multimodal bioimaging.Nanotechnology · 2011Article
- Induction of antitumor immunity by dendritic cells loaded with membrane-translocating mucin 1 Peptide antigen.Translational oncology · 2011Article
- Functionalization of iron oxide nanoparticles with a versatile epoxy amine linker.Journal of materials chemistry · 2010Article
- Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine.International journal of nanomedicineArticle
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
We report the development of superparamagnetic iron oxide (SPIOs) nanoparticles and investigate the migration of SPIO-labeled dendritic cells (DCs) in a syngeneic mouse model using magnetic resonance (MR) imaging. The size of the dextran-coated SPIO is roughly 30 nm, and the DCs are capable of independent uptake of these particles, although not at levels comparable to particle uptake in the presence of a transfecting reagent. On average, with the assistance of polylysine, the particles were efficiently delivered inside DCs within one hour of incubation. The SPIO particles occupy approximately 0.35% of cell surface and are equivalent to 34.6 pg of iron per cell. In vivo imaging demonstrated that the labeled cells migrated from the injection site in the footpad to the corresponding popliteal lymph node. The homing of labeled cells in the lymph nodes resulted in a signal drop of up to 79%. Furthermore, labeling DCs with SPIO particles did not compromise cell function, we demonstrated that SPIO-enhanced MR imaging can be used to track the migration of DCs effectively in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.