ArticleInternational journal of diabetes in developing countries2010
Effects of physical training on the immune system in diabetic rats.
Article in International journal of diabetes in developing countries, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Physical Activity and Risk of Colon Cancer in Diabetic and Nondiabetic US Adults.Mayo Clinic proceedings · 2016Article
- Article
- Influence of the use of testosterone associated with physical training on some hematologic and physical parameters in older rats with alloxan-induced diabetes.Archives of endocrinology and metabolismArticle
- The Effects of Testosterone Therapy Combined with Swimming Exercise on Adipose Tissue and Biochemical Parameters in Male Obese Wistar Rats.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
4 authors.
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Abstract
aimsThis study aims to investigate the influence of physical training on the immune system of diabetic rats. MATERIALS AND
methodsAdult male Wistar rats were distributed into Sedentary Control (SC), Trained Control (TC), Sedentary Diabetic (SD) and Trained Diabetic (TD) groups were used. Diabetes was induced by alloxan (32 mg/bw-i.v.). Training protocol consisted of swimming, at 32 +/- 1 degrees C, one hour/day, five days/week, supporting an overload equivalent to 5% of the body weight, during four weeks. At the end of the experiment the rats were sacrificed by decapitation and blood samples were collected for glucose, insulin, albumin, hematocrit determinations, total and differential leukocyte counting. Additionally, liver samples for glycogen analyses were obtained.
resultsThe results were analyzed by one way at a significance level of 5%. Diabetes reduced blood insulin, liver glycogen stores and increased blood glucose and neutrophil count. Physical training restored glycemia, liver glycogen levels, neutrophils and lymphocytes count in diabetic rats.
conclusionsIn summary, physical training was able to improve metabolic and immunological aspects in the experimental diabetic rats.
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