ArticleGut and liver2009
Adult celiac disease and its malignant complications.
Article in Gut and liver, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Colonic neoplasia and celiac disease: A systematic review.World journal of gastroenterology · 2025Pooled it
- Guideline
- Therapeutic TG2 inhibition reverses systemic multiomic dysregulation in celiac disease.BMC medicine · 2026Trial
- Article
- Associations of Clinical Presentation of Coeliac Disease with Comorbidities and Complications: A Retrospective Single-Centre Analysis.Journal of personalized medicine · 2025Article
- Celiac disease: mechanisms and emerging therapeutics.Trends in pharmacological sciences · 2023Review
- The Role of Physicians' Factors in Underdiagnosis of Celiac Disease in the Eastern Province of Saudi Arabia.Cureus · 2023Article
- Cerebellar presence of immune cells in patients with neuro-coeliac disease.Acta neuropathologica communications · 2023Article
- Spontaneous Latency in Adult Patients with Celiac Disease on a Normal Diet after Gluten-Free Diet: Case Series.Middle East journal of digestive diseases · 2022Article
- Association between intestinal neoplasms and celiac disease: A review.World journal of gastrointestinal oncology · 2021Review
- Raman Spectroscopy Technique: A Non-Invasive Tool in Celiac Disease Diagnosis.Diagnostics (Basel, Switzerland) · 2021Article
- Black Race and Public Insurance Are Predictive of Inappropriate Evaluation of Iron Deficiency Anemia and Diarrhea.Digestive diseases and sciences · 2021Article
- Development of the Dietitian Integrated Evaluation Tool for Gluten-free Diets (DIET-GFD).Nutrition (Burbank, Los Angeles County, Calif.) · 2020Article
- An updated overview of spectrum of gluten-related disorders: clinical and diagnostic aspects.BMC gastroenterology · 2020Review
- Association between grains, gluten and the risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort.European journal of nutrition · 2020Article
- Refractory Celiac Disease Type II: A Case Report and Literature Review.Frontiers in medicine · 2020Article
- Gluten-Free Diet: Gaps and Needs for a Healthier Diet.Nutrients · 2019Review
- Lack of health care professional's awareness for management of celiac disease may contribute to the under diagnosis of celiac disease.Gastroenterology and hepatology from bed to bench · 2019Article
- Perspective: Gluten-Free Products for Patients with Celiac Disease Should Not Contain Trace Levels.Advances in nutrition (Bethesda, Md.) · 2017Article
- The association between socioeconomic status and the symptoms at diagnosis of celiac disease: a retrospective cohort study.Therapeutic advances in gastroenterology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adult celiac disease is a chronic intestinal disorder that has been estimated to affect up to 1-2% of the population in some nations. Awareness of the disease has increased, but still it remains markedly underdiagnosed. Celiac disease is a pathologically defined condition with several characteristic clinical scenarios that should lead the clinician to suspect its presence. Critical to diagnosis is a documented responsiveness to a gluten-free diet. After diagnosis and treatment, symptoms and biopsy-proven changes may recur and appear refractory to a gluten-free diet. Recurrent symptoms are most often due to poor diet compliance, a ubiquitous and unrecognized gluten source, an initially incorrect diagnosis, or an associated disease or complication of celiac disease. Some patients with persistent symptoms and biopsy-proven changes may not have celiac disease at all, instead suffering from a sprue-like intestinal disease, so-called unclassified sprue, which is a specific entity that does not appear to respond to a gluten-free diet. Some of these patients eventually prove to have an underlying malignant cause, particularly lymphoma. The risk of developing lymphoma and other malignancies is increased in celiac disease, especially if initially diagnosed in the elderly, or late in the clinical course of the disease. However, recent studies suggest that the risk of gastric and colon cancer is low. This has led to the hypothesis that untreated celiac disease may be protective, possibly due to impaired absorption and more rapid excretion of fat or fat-soluble agents, including hydrocarbons and other putative cocarcinogens, which are implicated in the pathogenesis of colorectal cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.