ArticleNature protocols2010
Production of mice using iPS cells and tetraploid complementation.
Article in Nature protocols, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Stra8 links neuronal activity to inhibitory circuit protection in the adult mouse brain.Cell reports · 2025Article
- Rapid generation of murine haploid-induced trophoblast stem cellsSTAR protocols · 2021Article
- A single-cell identification and capture chip for automatically and rapidly determining hydraulic permeability of cells.Analytical and bioanalytical chemistry · 2020Article
- Effect of Exogenous Transcription Factors Integration Sites on Safety and Pluripotency of Induced Pluripotent Stem Cells.Balkan journal of medical genetics : BJMG · 2020Article
- Urine-Derived Induced Pluripotent Stem Cells in Cardiovascular Disease.Cardiology research and practice · 2020Review
- Induced Pluripotent Stem Cells: Reprogramming Platforms and Applications in Cell Replacement Therapy.BioResearch open access · 2020Article
- Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining.Cancer communications (London, England) · 2018Article
- Some Ethical Concerns About Human Induced Pluripotent Stem Cells.Science and engineering ethics · 2016Article
- Techniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell Derivation.Archivum immunologiae et therapiae experimentalis · 2016Review
- Comparison of intracerebral transplantation effects of different stem cells on rodent stroke models.Cell biochemistry and function · 2015Article
- Tetraploid complementation proves pluripotency of induced pluripotent stem cells derived from adipose tissue.Cell proliferation · 2015Article
- Application of Induced Pluripotent Stem Cells in Liver Diseases.Cell medicine · 2014Review
- Potential and Challenges of Induced Pluripotent Stem Cells in Liver Diseases Treatment.Journal of clinical medicine · 2014Review
- Deep sequencing reveals low incidence of endogenous LINE-1 retrotransposition in human induced pluripotent stem cells.PloS one · 2014Article
- Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference.PloS one · 2014Article
- Accelerating cancer modeling with RNAi and nongermline genetically engineered mouse models.Cold Spring Harbor protocols · 2013Review
- Mechanisms and models of somatic cell reprogramming.Nature reviews. Genetics · 2013Review
- Article
- A pipeline for the generation of shRNA transgenic mice.Nature protocols · 2012Article
- Rapid conversion of human ESCs into mouse ESC-like pluripotent state by optimizing culture conditions.Protein & cell · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Induced pluripotent stem cells (iPSCs) are considered to be an attractive alternative to embryonic stem cells (ESCs) and may provide great potential for clinical applications in regenerative medicine. Although possessing characteristics similar to ESCs, the true pluripotency of these newly studied iPSCs was not known because none of the previously developed iPSCs passed the tetraploid complementation assay, which is regarded as the most stringent test for pluripotency. We have recently shown that by modifying some of the culture conditions for inducing iPSCs, we were able to generate cell lines of high pluripotency, resulting in the production of live-born, fertile animals through tetraploid complementation. In this paper, we describe details of our methods of generating iPS cell lines and subsequently producing full-term live animals through the tetraploid complementation assay; the procedure can be completed within 2 months.
Indexed as
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20431542What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.