Evidence map›Paper›PMID 20430952›Full record

ReviewPhysiology (Bethesda, Md.)2010

Lessons from photoreceptors: turning off g-protein signaling in living cells.

Marie E Burns, Edward N Pugh

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. E122Q rhodopsin: pigment microspectrophotometry, photoreceptor light responses, and bleaching adaptation.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Article
  2. Article
  3. Review
  4. Reproducibility of the Rod Photoreceptor Response Depends Critically on the Concentration of the Phosphodiesterase Effector Enzyme.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Sperm Sensory Signaling.Cold Spring Harbor perspectives in biology · 2017
    Review
  18. Why are rods more sensitive than cones?The Journal of physiology · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marie E BurnsDepartments of Ophthalmology and Vision Science, University of California, Davis, California, USA. meburns@ucdavis.edu
Edward N Pugh

Funding

MECHANISMS OF VISUAL TRANSDUCTIONR01EY002660 · NEI · UNIVERSITY OF PENNSYLVANIA · PI PUGH, EDWARD N · 1985 to 2021
$11.4M
Deactivation Mechanisms of Rod PhototransductionR01EY014047 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI BURNS, MARIE E · 2002 to 2020
$8.5M
NEI NIH HHS R01 EY002660NEI NIH HHS R01 EY014047
6 · The paper itself

Abstract

Phototransduction in retinal rods is one of the most extensively studied G-protein signaling systems. In recent years, our understanding of the biochemical steps that regulate the deactivation of the rod's response to light has greatly improved. Here, we summarize recent advances and highlight some of the remaining puzzles in this model signaling system.

Indexed as

AnimalsGTP-Binding ProteinsMiceRetinal Rod Photoreceptor CellsVision, OcularGTP-Binding Proteins

Identifiers

PMID20430952
PMCPMC2880230

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.