ReviewJournal of communication disorders
Future approaches for inner ear protection and repair.
Review in Journal of communication disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- From Anatomy to Application: A Comprehensive Review of Nanovesicular Systems for Otic Drug Delivery.AAPS PharmSciTech · 2026Review
- A single dose of AC102 restores hearing in a guinea pig model of noise-induced hearing loss to almost prenoise levels.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification.PLoS biology · 2023Article
- Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea.Scientific reports · 2020Article
- Research progress on flat epithelium of the inner ear.Physiological research · 2020Review
- Targeted Allele Suppression Prevents Progressive Hearing Loss in the Mature Murine Model of Human TMC1 Deafness.Molecular therapy : the journal of the American Society of Gene Therapy · 2019Article
- Enhanced viral-mediated cochlear gene delivery in adult mice by combining canal fenestration with round window membrane inoculation.Scientific reports · 2018Article
- Intravenous rAAV2/9 injection for murine cochlear gene delivery.Scientific reports · 2017Article
- Congenital hearing loss.Nature reviews. Disease primers · 2017Review
- Neuroglobin immunoreactivity in the human cochlea.Brain research · 2016Article
- Otology Jubilee: 150 years of the Archiv für Ohrenheilkunde "Where do we come from?--Where are we?--Where are we going?".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015Article
- Changes in the adult vertebrate auditory sensory epithelium after trauma.Hearing research · 2013Review
- The convergence of cochlear implantation with induced pluripotent stem cell therapy.Stem cell reviews and reports · 2012Review
- Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Hearing loss: a common disorder caused by many rare alleles.Annals of the New York Academy of Sciences · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
unlabelledHealth care professionals tending to patients with inner ear disease face inquiries about therapy options, including treatments that are being developed for future use but not yet available. The devastating outcome of sensorineural hearing loss, combined with the permanent nature of the symptoms, make these inquiries demanding and frequent. The vast information accessible online and the publicity for breakthroughs in research add to patient requests for access to advanced and innovative therapies, even before these are available for clinical use. This can sometimes be taxing on the health care provider who is in contact with the patients. Here we aim to equip the provider with information about some of the progress made for protective and reparative approaches for treating inner ears. LEARNING OUTCOMES: (1) Readers will be able to explain why hearing loss is irreversible and common, (2) readers will be able to explain the importance of protective measures and the progress made in discovery and design of novel biological protective molecules, (3) readers will be able to describe reparative approaches currently under investigation (such as tissue engineering), the main difficulties in the design of such therapies and the major hurdles that remain for making novel technologies clinically viable, and (4) readers will be able to explain to their patients some of the progress in developing new treatments without making the promise of imminent clinical use. With this information, readers will be able to guide patients to make better choices for their treatment and to guide students toward research in this exciting field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.