ArticleBMC ecology2010
Differential expression of the heat shock protein Hsp70 in natural populations of the tilapia, Sarotherodon melanotheron, acclimatised to a range of environmental salinities.
Article in BMC ecology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 92 citations in OpenAlex.
- Pathological, immunohistochemical and molecular studies on rutin's protective effects against water hardness-induced cytotoxicity in Nile tilapia, Oreochromis niloticus.Journal of fish biology · 2026Article
- Alternative Splicing and Gene Expression Variation Underlie Population and Life History Differences in an Amphibian.Ecology and evolution · 2025Article
- Unravelling the hsp70 gene in snubnose pompano (Trachinotus blochii): insights into stress response mechanisms.Fish physiology and biochemistry · 2025Article
- Investigating the mechanism of heat-shock protection in ISKNV-infected tilapia brain cell line.Microbiology spectrum · 2025Article
- Salinity Tolerance in Freshwater Drum (Animals : an open access journal from MDPI · 2025Article
- A Review on the Involvement of Heat Shock Proteins (Extrinsic Chaperones) in Response to Stress Conditions in Aquatic Organisms.Antioxidants (Basel, Switzerland) · 2023Review
- Seasonal variation in the expression pattern of heat shock protein 70 and 90 in Common carp (Veterinary research forum : an international quarterly journal · 2023Article
- Effects of exposure to environmentally relevant concentrations of lead (Pb) on expression of stress and immune-related genes, and microRNAs in shorthorn sculpins (Myoxocephalus scorpius).Ecotoxicology (London, England) · 2022Article
- Salinity significantly affects intestinal microbiota and gene expression in striped catfish juveniles.Applied microbiology and biotechnology · 2022Article
- The time course of molecular acclimation to seawater in a euryhaline fish.Scientific reports · 2021Article
- Oxytocin Signaling Acts as a Marker for Environmental Stressors in Zebrafish.International journal of molecular sciences · 2021Article
- Population differences in Chinook salmon (Ecology and evolution · 2021Article
- Genome-wide analysis of European sea bass provides insights into the evolution and functions of single-exon genes.Ecology and evolution · 2021Article
- Effects of Sudden Drop in Salinity on Osmotic Pressure Regulation and Antioxidant Defense Mechanism ofFrontiers in physiology · 2020Article
- Article
- A field and laboratory study of the responses of cytoprotection and osmoregulation to salinity stress in mosquitofish (Gambusia affinis).Fish physiology and biochemistry · 2018Article
- Transport Stress Changes Blood Biochemistry, Antioxidant Defense System, and Hepatic HSPs mRNA Expressions of Channel CatfishFrontiers in physiology · 2018Article
- Proteomic Analysis of the Chlorophyta Dunaliella New Strain AL-1 Revealed Global Changes of Metabolism during High Carotenoid Production.Marine drugs · 2017Article
- Evidence of the Complexity of Gene Expression Analysis in Fish Wild Populations.International journal of genomics · 2017Article
- Conserved effects of salinity acclimation on thermal tolerance and hsp70 expression in divergent populations of threespine stickleback (Gasterosteus aculeatus).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between environmental variation and induction of heat shock proteins (Hsps) has been much documented under experimental conditions. However, very little is known about such induction in natural populations acclimatised to prevailing environmental conditions. Furthermore, while induction of stress proteins has been well documented in response to environmental contaminants and thermal stressors, little is known about whether factors, such as extreme salinity, are also potential inductors. The black-chinned tilapia Sarotherodon melanotheron is unusual for its ability to colonise estuarine environments in West Africa that are characterised by extremely high salinities. The relationships between mRNA levels of the 70 kDa heat shock protein (Hsp70) and Na+, K+-ATPase1alpha (Naka) in the gills, environmental salinity, and a life-history trait (condition factor) were investigated in wild populations of this species sampled from three locations in the Saloum estuary, at salinities ranging from 40 to 100 psu.
resultsThe highest Hsp70 and Naka mRNA levels, and the poorest condition factors were recorded in the most saline sampling site (100 psu). The Hsp70 and Naka mRNA were correlated amongst themselves and showed a direct positive correlation with environmental salinity, and a negative correlation with fish condition factor. Thus, the Hsp70 is constitutively overexpressed by S. melanotheron acclimatised to extreme hypersalinity.
conclusionsThese results indicate that, although S. melanotheron can colonise extremely saline environments, the overexpression of Hsp70 combined with the higher Naka mRNA expression reveals that this represents a chronic stress. The induction of Hsp70 was, therefore, a biomarker of chronic hyper-osmotic stress which presumably can be linked to the impaired growth performance and precocious reproduction that have been demonstrated in the populations at the extremely saline sites.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.