Evidence map›Paper›PMID 20429829›Full record

ReviewJournal of receptor and signal transduction research2010

On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers.

Luigi F Agnati, Diego Guidolin, Jean Pierre Vilardaga, Francisco Ciruela, Kjell Fuxe

Abstract readReview
In one paragraph

Review in Journal of receptor and signal transduction research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

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  8. Allosteric Interactions between Adenosine AInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Luigi F AgnatiIRCCS San Camillo, Lido Venezia, Italy. luigiagnati@tin.it
Diego Guidolin
Jean Pierre Vilardaga
Francisco Ciruela
Kjell Fuxe
Institut d'Investigació Biomédica de Bellvitge · ESIRCCS San Camillo Hospital · ITKarolinska Institutet · SEMassachusetts General Hospital · USUniversity of Padua · IT

Funding

Sustained cAMP Signals Triggered by Internalized PTH Receptor: New Consequences fR01DK087688 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VILARDAGA, JEAN-PIERRE · 2010 to 2014
$1.6M
NIDDK NIH HHS R01 DK087688
6 · The paper itself

Abstract

The oligomerization of G protein-coupled receptors (GPCRs) is a fact that deserves further attention as increases both the complexity and diversity of the receptor-mediated signal transduction, thus enriching the cell signaling. Consequently, in the present review we tackle among others the problems concerning the terminology used to describe aspects surrounding the GPCRs oligomerization phenomenon. Therefore, the theoretical implications of the GPCR oligomerization will be briefly discussed together with possible implications of this phenomenon especially for new strategies in drug development.

Indexed as

Protein MultimerizationAnimalsCell LineCell MembraneModels, TheoreticalProtein ConformationReceptors, G-Protein-CoupledSignal TransductionReceptors, G-Protein-Coupled

Identifiers

PMID20429829
PMCPMC3595533
OpenAlexW2158920012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.