Trial reportInternational urogynecology journal2010
Anterior vaginal wall prolapse: a randomized controlled trial of SIS graft versus traditional colporrhaphy.
Trial report in International urogynecology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Transvaginal mesh or grafts or native tissue repair for vaginal prolapse.The Cochrane database of systematic reviews · 2024Pooled it
- A systematic review of outcome and outcome-measure reporting in randomised trials evaluating surgical interventions for anterior-compartment vaginal prolapse: a call to action to develop a core outcome set.International urogynecology journal · 2018Pooled it
- Anterior colporrhaphy: a standard operation? Systematic review of the technical aspects of a common procedure in randomized controlled trials.International urogynecology journal · 2018Pooled it
- Surgery for women with anterior compartment prolapse.The Cochrane database of systematic reviews · 2016Pooled it
- Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse.The Cochrane database of systematic reviews · 2016Pooled it
- Management of pelvic organ prolapse and quality of life: a systematic review and meta-analysis.International urogynecology journal · 2014Pooled it
- Genital prolapse in women.BMJ clinical evidence · 2012Pooled it
- No mesh versus mesh in the treatment of anterior vaginal wall prolapse: prospective, randomised, controlled trial, long-term follow-up.International urology and nephrology · 2020Trial
- Multicenter, randomized trial comparing native vaginal tissue repair and synthetic mesh repair for genital prolapse surgical treatment.International urogynecology journal · 2015Trial
- Sexual function after anterior vaginal wall prolapse surgery.Clinics (Sao Paulo, Brazil) · 2012Trial
- Shaping the future of urogynecology through regenerative medicine.Current opinion in obstetrics & gynecology · 2025Review
- Decellularization of Small Intestinal Submucosa.Advances in experimental medicine and biology · 2021Article
- Managing female pelvic floor disorders: a medical device review and appraisal.Interface focus · 2019Review
- Laparoscopic Sacrocolpopexy Plus Colporrhaphy With a Small Intestine Submucosa Graft Versus Total Pelvic Floor Reconstruction for Advanced Prolapse: A Retrospective Cohort Study.International neurourology journal · 2019Article
- Long-term active surveillance of implantable medical devices: an analysis of factors determining whether current registries are adequate to expose safety and efficacy problems.BMJ surgery, interventions, & health technologies · 2019Review
- Porcine Small Intestinal Submucosa Mesh for Treatment of Pelvic Organ Prolapsed.Chinese medical journal · 2016Article
- Recurrent pelvic organ prolapse: International Urogynecological Association Research and Development Committee opinion.International urogynecology journal · 2016Review
- 3-year results of transvaginal cystocele repair with transobturator four-arm mesh: A prospective study of 105 patients.Arab journal of urology · 2014Article
- Anterior colporrhaphy: why surgeon performance is paramount.International urogynecology journal · 2014Article
- Prevention and management of pelvic organ prolapse.F1000prime reports · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThis study seeks to compare the small intestine submucosa (SIS) graft with traditional colporrhaphy (TC) for surgical treatment of anterior vaginal prolapse.
methodsSubjects were randomly assigned to SIS (n = 29) or to TC (n = 27) preoperatively and outcomes analyzed at 12 months postoperatively. The primary outcome was the absence of POP-Q stage >or= II prolapse, and secondary outcome was improvement in quality of life. Data were compared with independent samples or paired Student's t test.
resultsSIS group had 86.2% anatomic cure compared to 59.3% in TC (p = 0.03). SIS improved point Ba measurement significantly (-1.93 cm versus -1.37 cm, p = 0.02). Both operations significantly improved quality of life, although there were no differences between the groups. We observed a greater number of complications in the SIS group, with no infections or erosion.
conclusionsSIS repair improved point Ba significantly. However, there were no differences observed in quality of life between the techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.