ArticleNeuroradiology2010
Congenital tumors of the central nervous system.
Article in Neuroradiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- Pediatrics supratentorial intraventricular atypical teratoid/rhabdoid tumors: a case report and a systematic review of the literature.European journal of pediatrics · 2026Pooled it
- Case Report: Imaging features of fetal intracranial immature teratoma.Frontiers in oncology · 2026Article
- Report from the National Pediatric Cancer Foundation - infantile glioma and other non-embryonal central nervous system tumors: evolving molecular advances and current treatment landscape.Frontiers in oncology · 2026Review
- Bilateral Sylvian fissure lipomas with angiomatous component: A case report.Radiology case reports · 2025Article
- Prenatal diagnosis of Pallister-Hall syndrome: ultrasound, magnetic resonance imaging, and three-dimensional reconstructions of phenotypical findings.Journal of ultrasound · 2025Article
- Long-term prognosis and treatment outcomes in infantile and neonatal brain tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Congenital extraventricular neurocytoma with atypical features in a 3-day-old neonate.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Approaches to supratentorial brain tumours in children.Neuroradiology · 2024Review
- Imaging of supratentorial intraventricular masses in children:a pictorial review- part 1.Neuroradiology · 2024Review
- Central nervous system tumours in neonates: what should the neonatologist know?European journal of pediatrics · 2024Review
- Modeling human brain rhabdoid tumor by inactivating tumor suppressor genes in induced pluripotent stem cells.Bioactive materials · 2024Article
- Fetal Brain Tumors, a Challenge in Prenatal Diagnosis, Counselling, and Therapy.Journal of clinical medicine · 2022Article
- Gliomas in children and adolescents: investigation of molecular alterations with a potential prognostic and therapeutic impact.Journal of cancer research and clinical oncology · 2022Article
- Infantile Brain Tumors: A Review of Literature and Future Perspectives.Diagnostics (Basel, Switzerland) · 2021Review
- Congenital tumors of the central nervous system: an institutional review of 64 cases with emphasis on tumors with unique histologic and molecular characteristics.Brain pathology (Zurich, Switzerland) · 2021Article
- Imaging of fetal brain tumors.Pediatric radiology · 2020Review
- Imaging of fetal ventriculomegaly.Pediatric radiology · 2020Review
- Infantile/Congenital High-Grade Gliomas: Molecular Features and Therapeutic Perspectives.Diagnostics (Basel, Switzerland) · 2020Review
- Congenital Extra-Ventricular (Ganglio)Neurocytoma of the Brain Stem: A Case Report.Frontiers in pediatrics · 2018Article
- Congenital craniopharyngioma treated by radical surgery: case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital tumors of the central nervous system (CNS) are often arbitrarily divided into "definitely congenital" (present or producing symptoms at birth), "probably congenital" (present or producing symptoms within the first week of life), and "possibly congenital" (present or producing symptoms within the first 6 months of life). They represent less than 2% of all childhood brain tumors. The clinical features of newborns include an enlarged head circumference, associated hydrocephalus, and asymmetric skull growth. At birth, a large head or a tense fontanel is the presenting sign in up to 85% of patients. Neurological symptoms as initial symptoms are comparatively rare. The prenatal diagnosis of congenital CNS tumors, while based on ultrasonography, has significantly benefited from the introduction of prenatal magnetic resonance imaging studies. Teratomas constitute about one third to one half of these tumors and are the most common neonatal brain tumor. They are often immature because of primitive neural elements and, rarely, a component of mixed malignant germ cell tumors. Other tumors include astrocytomas, choroid plexus papilloma, primitive neuroectodermal tumors, atypical teratoid/rhabdoid tumors, and medulloblastomas. Less common histologies include craniopharyngiomas and ependymomas. There is a strong predilection for supratentorial locations, different from tumors of infants and children. Differential diagnoses include spontaneous intracranial hemorrhage that can occur in the presence of coagulation factor deficiency or underlying vascular malformations, and congenital brain malformations, especially giant heterotopia. The prognosis for patients with congenital tumors is generally poor, usually because of the massive size of the tumor. However, tumors can be resected successfully if they are small and favorably located. The most favorable outcomes are achieved with choroid plexus tumors, where aggressive surgical treatment leads to disease-free survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.