Evidence map›Paper›PMID 20428092›Full record

ArticleNature genetics2010

Chipping away at the genetics of smoking behavior.

Christopher I Amos, Margaret R Spitz, Paul Cinciripini

Abstract readComment
In one paragraph

Article in Nature genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Coronary artery disease and cancer: a significant resemblance.Medical oncology (Northwood, London, England) · 2022
    Review
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Article
  10. Working to Eliminate Cancer Health Disparities from Tobacco: A Review of the National Cancer Institute's Community Networks Program.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Christopher I AmosDepartments of Epidemiology and Behavioral Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. camos@mdanderson.org
Margaret R Spitz
Paul Cinciripini

Funding

Transdisciplinary Research in Cancer of the Lung (TRICL)U19CA148127 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI AMOS, CHRISTOPHER I., LE MARCHAND, LOIC · 2010 to 2014
$10.9M
NCI NIH HHS U19 CA148127
6 · The paper itself

Abstract

Three large consortia present comprehensive analyses that identify genetic factors influencing smoking initiation, intensity and cessation. The genetic architecture of these three phases of smoking behavior appears to be largely distinct.

Indexed as

Chromosome MappingFamily HealthHealth BehaviorHumansModels, GeneticNicotinePharmacogeneticsReceptors, NicotinicSequence Analysis, DNASmokingSmoking CessationTobacco Use DisorderTwin Studies as TopicNicotineReceptors, Nicotinic

Identifiers

PMID20428092
PMCPMC6375692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.