Evidence map›Paper›PMID 20427693›Full record

ArticleJournal of clinical microbiology2010

International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma.

Claire Ham, Priya Srinivasan, Rigmor Thorstensson, Ernst Verschoor, Zahra Fagrouche, Leonardo Sernicola, Artur Ramos, Fausto Titti, Neil Almond, Neil Berry

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Variable BaselineFrontiers in immunology · 2019
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Claire HamDivision of Retrovirology, NIBSC/HPA, South Mimms, Potters Bar, Hertfordshire, United Kingdom.
Priya Srinivasan
Rigmor Thorstensson
Ernst Verschoor
Zahra Fagrouche
Leonardo Sernicola
Artur Ramos
Fausto Titti
Neil Almond
Neil Berry

Funding

Medical Research Council G0600007Medical Research Council G0601201Medical Research Council G9025730Medical Research Council G9419998
6 · The paper itself

Abstract

An international multicenter study was conducted to assess the performance of a panel of simian immunodeficiency virus (SIV) RNA reference materials for plasma viral load determinations. Reliable quantification was demonstrated across an approximately 6 log(10) dynamic range. Availability of external reference materials will enable independent calibration of SIV plasma viral load assays.

Indexed as

AnimalsLinear ModelsMacaca fascicularisReference StandardsReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionRNA, ViralSensitivity and SpecificitySimian Immunodeficiency VirusRNA, Viral

Identifiers

PMID20427693
PMCPMC2897500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.