Evidence map›Paper›PMID 20427517›Full record

ArticleBioinformatics (Oxford, England)2010

Semantic integration of data on transcriptional regulation.

Michael Baitaluk, Julia Ponomarenko

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Enabling semantic queries across federated bioinformatics databases.Database : the journal of biological databases and curation · 2019
    Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael BaitalukSan Diego Supercomputer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. baitaluk@sdsc.edu
Julia Ponomarenko

Funding

BiologicalNetworks: Integrated Environment for Systems BiologyR01GM084881 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAITALUK, MICHAEL · 2008 to 2011
$1.7M
Transcription Factor-DNA Interactions: Structural Classification and PredictionR01GM085325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PONOMARENKO, JULIA VLADIMIROVNA · 2008 to 2011
$1.1M
NIGMS NIH HHS R01 GM084881NIGMS NIH HHS R01GM084881NIGMS NIH HHS R01 GM085325NIGMS NIH HHS R01GM085325
6 · The paper itself

Abstract

motivationExperimental and predicted data concerning gene transcriptional regulation are distributed among many heterogeneous sources. However, there are no resources to integrate these data automatically or to provide a 'one-stop shop' experience for users seeking information essential for deciphering and modeling gene regulatory networks.

resultsIntegromeDB, a semantic graph-based 'deep-web' data integration system that automatically captures, integrates and manages publicly available data concerning transcriptional regulation, as well as other relevant biological information, is proposed in this article. The problems associated with data integration are addressed by ontology-driven data mapping, multiple data annotation and heterogeneous data querying, also enabling integration of the user's data. IntegromeDB integrates over 100 experimental and computational data sources relating to genomics, transcriptomics, genetics, and functional and interaction data concerning gene transcriptional regulation in eukaryotes and prokaryotes. AVAILABILITY: IntegromeDB is accessible through the integrated research environment BiologicalNetworks at http://www.BiologicalNetworks.org CONTACT: baitaluk@sdsc.edu SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Gene Expression RegulationComputational BiologyGene Regulatory NetworksTranscription, Genetic

Identifiers

PMID20427517
PMCPMC2887046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.